EX-99.2 3 d886079dex992.htm EX-99.2 EX-99.2

Exhibit 99.2

 

LOGO

 

- 1 -


CONSOLIDATED INTERIM BALANCE SHEET

(unaudited)

 

in CHF thousands

   Notes      June 30,
2024
    December 31,
2023
 

ASSETS

       

Intangible assets

     6        53,393       54,414  

Right-of-use assets

     7        2,363       2,570  

Property and equipment

        338       397  

Other non-current assets

        116       116  

Deferred tax assets

     22        —        589  
     

 

 

   

 

 

 

Non-current assets

        56,210       58,086  

Inventories

     8        374       557  

Trade receivables

        964       1,171  

Other current assets

     9        2,645       2,020  

Cash and cash equivalents

        10,728       14,556  
     

 

 

   

 

 

 

Current assets

        14,711       18,304  
     

 

 

   

 

 

 

Total assets

        70,921       76,390  
     

 

 

   

 

 

 

EQUITY AND LIABILITIES

       

Share capital

     10        1,404       56,163  

Reserves

        270,799       220,330  

Treasury shares

        (150     (6,001

Accumulated losses

        (222,786     (218,264
     

 

 

   

 

 

 

Equity

        49,267       52,228  
     

 

 

   

 

 

 

Non-current lease liabilities

     7        2,019       2,086  

Non-current borrowings

        —        9  

Defined benefit obligations

     11        1,072       1,589  

Provisions

     12        6,465       6,203  

Deferred tax liabilities

        7,335       7,366  
     

 

 

   

 

 

 

Non-current liabilities

        16,891       17,253  

Current lease liabilities

     7        386       524  

Current borrowings

        12       337  

Trade payables

        1,291       1,025  

Financial liabilities due to related parties

     13        —        1,355  

Provisions

     12        —        235  

Other current payables and liabilities

     14        3,074       3,433  
     

 

 

   

 

 

 

Current liabilities

        4,763       6,909  
     

 

 

   

 

 

 

Total equity and liabilities

        70,921       76,390  
     

 

 

   

 

 

 

The accompanying notes form an integral part of these consolidated interim financial statements.

 

- 2 -


CONSOLIDATED INTERIM STATEMENT OF COMPREHENSIVE LOSS

(unaudited)

 

          Six-month period ended June 30,  

in CHF thousands

   Notes    2024     2023  

Revenue

   5      5,581       3,023  

Other gains

   15      73       66  
     

 

 

   

 

 

 

Total income

        5,654       3,089  

Raw materials and consumables expenses

   16      (1,562     (779

External selling and distribution expenses

   16      (398     (1,442

External research and development expenses

   17      (733     (933

Personnel expenses

   18      (3,484     (6,259

Other administrative expenses

   19      (2,017     (3,462
     

 

 

   

 

 

 

EBITDA

        (2,540     (9,786

Change in fair value of contingent consideration

   12      —        3,962  

Impairment expense

   6      —        (55,824

Amortization and depreciation expense

   20      (1,438     (1,704
     

 

 

   

 

 

 

Operating result

        (3,978     (63,352

Financial income

   21      200       —   

Financial expense

   21      (219     (790
     

 

 

   

 

 

 

Net loss before taxes

        (3,997     (64,142

Income taxes

   22      (560     7,643  
     

 

 

   

 

 

 

Net loss for the period

        (4,557     (56,499

OTHER COMPREHENSIVE INCOME

       

Remeasurement of defined benefit obligations

        35       —   
     

 

 

   

 

 

 

Items that will not be reclassified to profit or loss

        35       —   

Currency translation differences

        (32     415  
     

 

 

   

 

 

 

Items that may be reclassified to profit or loss

        (32     415  
     

 

 

   

 

 

 

Other comprehensive income for the period, net of tax

        3       415  
     

 

 

   

 

 

 

Total comprehensive loss for the period

        (4,554     (56,084
     

 

 

   

 

 

 

EARNINGS PER SHARE

       

Basic and diluted loss per share (in CHF)

   23      (0.363     (5.098

The accompanying notes form an integral part of these consolidated interim financial statements.

 

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CONSOLIDATED INTERIM STATEMENT OF CASH FLOW

(unaudited)

 

            Six-month period ended June 30,  

in CHF thousands

   Notes      2024     2023  

Net loss for the period

        (4,557     (56,499

Adjustments:

       

Income tax

     22        560       (7,643

Amortization and depreciation expense

     20        1,438       1,704  

Impairment of intangible assets

        —        55,734  

Impairment of receivables and inventories

        —        98  

Reversal of impairment

        (7     —   

Gain from fair value adjustments on contingent liabilities

        —        (3,962

Finance expenses, net

     21        56       535  

Change in defined benefit obligations

     11        (483     —   

Share-based payment expense

        225       511  

Changes in working capital:

       

Decrease/(Increase) in inventories

        183       (223

Decrease/(Increase) in trade receivables

        214       301  

Decrease/(Increase) in other assets

        (626     (312

(Decrease)/Increase in trade payables

        266       577  

(Decrease)/Increase in provisions

        (79     (136

(Decrease)/Increase in other payables and liabilities

        (356     (1,151
     

 

 

   

 

 

 

Cash flow used in operating activities

        (3,166     (10,466
     

 

 

   

 

 

 

Payments for property, plant and equipment

        —        (369

Payments for intangible assets

     6        (86     —   

Proceeds from acquisition price adjustment of intangible assets

        —        149  

Interest received

     21        79       —   
     

 

 

   

 

 

 

Cash flow from (used in) investing activities

        (7     (220
     

 

 

   

 

 

 

Proceeds from capital increases

        —        4,992  

Sale of treasury shares

        —        17  

Equity transaction costs

        —        (487

Repayment of lease liabilities

        (271     (344

Repayment of borrowings

        (345     (4
     

 

 

   

 

 

 

Cash flow from (used in) financing activities

        (616     4,174  
     

 

 

   

 

 

 

Net decrease in cash and cash equivalents

        (3,789     (6,512

Cash and cash equivalents at beginning of period

        14,556       19,237  

Exchange difference on cash and cash equivalents

        (39     67  

Cash and cash equivalents at end of period

        10,728       12,792  

The accompanying notes form an integral part of these consolidated interim financial statements.

 

- 4 -


CONSOLIDATED INTERIM STATEMENT OF CHANGES IN EQUITY

(unaudited)

 

in CHF thousands

   Share
capital
    Treasury
shares
    Reserves     Accumulated
loss
    Total
equity
 

Balance at January 1, 2023

     56,163       (12,108     220,961       (119,599     145,417  

Result for the period

     —        —        —        (56,499     (56,499

Other comprehensive income for the period

     —        —        415       —        415  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Total comprehensive result for the period

     —        —        415       (56,499     (56,084
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Direct Share Placement program

     —        12       5       —        17  

Private placement

     —        4,800       195       —        4,995  

Withdrawal of fractional shares

     —        (12     (10     —        (22

Capital increase transaction costs

     —        —        (487     —        (487

Exercise of options

     —        19       —        —        19  

Share-based compensation cost

     —        —        511       —        511  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Balance at June 30, 2023

     56,163       (7,289     221,590       (176,098     94,366  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Balance at January 1, 2024

     56,163       (6,001     220,330       (218,264     52,228  

Result for the period

     —        —        —        (4,557     (4,557

Other comprehensive income for the period

     —        —        (32     35       3  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Total comprehensive result for the period

     —        —        (32     (4,522     (4,554
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Nominal value reduction (note 10)

     (54,759     5,851       48,908       —        —   

Share-based compensation cost

     —        —        225       —        225  

Issuance of warrants (note 13)

     —        —        1,368       —        1,368  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Balance at June 30, 2024

     1,404       (150     270,799       (222,786     49,267  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

The accompanying notes form an integral part of these consolidated interim financial statements.

 

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NOTES TO THE CONSOLIDATED INTERIM FINANCIAL STATEMENTS

1. General information

RELIEF THERAPEUTICS Holding SA (“Relief”, the “Company” or the “Group”) is a Swiss stock corporation domiciled at 15 Avenue de Sécheron, 1202 Geneva, Switzerland. The Company’s shares are listed on the SIX Swiss Exchange (ticker: RLF) and quoted in the U.S. on OTCQB (tickers: RLFTF, RLFTY).

The Group focuses on the identification, development and commercialization of novel, patent protected products intended for the treatment of dermatological, metabolic, and pulmonary rare diseases with a portfolio of clinical and marketed products that serve unmet patient needs.

In March 2021, Relief signed a collaboration and license agreement with Acer Therapeutics, Inc. (“Acer”) for the worldwide development and commercialization of ACER-001 (OLPRUVA®) for the treatment of urea cycle disorders (“UCDs”) and maple syrup urine disease (“MSUD”). In December 2022, the FDA approved OLPRUVA for the treatment of UCDs in the U.S. In August 2023, Relief and Acer terminated the March 2021 collaboration and license agreement and entered into a new exclusive license agreement for the development and commercialization of OLPRUVA for the treatment of UCDs, MSUD, and other potential indications. Under the terms of the new agreement, Acer retains development and commercialization rights worldwide, excluding Europe where Relief retains these rights. Relief was entitled to receive from Acer a 10% continuing royalty on net sales of OLPRUVA in the Acer territory (worldwide, excluding Europe), and 20% of any value received by Acer from licensing or divestment transactions relating to OLPRUVA, up to a cumulative amount of USD 45 million (CHF 40.4 million). In August 2024 (post-reporting period), Relief sold its royalty entitlement to SWK, subject to certain terms and conditions (note 26).

In June 2021, Relief acquired APR Applied Pharma Research SA (“APR”), a privately held Swiss pharmaceutical company specialized in formulating, developing, and commercializing known molecules designed with proprietary drug delivery systems for niche and specialty diseases. The acquisition transformed the Company into a fully integrated commercial-stage biopharmaceutical group. The acquisition further diversified Relief’s pipeline and portfolio with both commercial products and clinical-stage programs, provided a commercial infrastructure in Europe, and strengthened internal research and development capabilities. The same year, Relief acquired AdVita Lifescience GmbH (“AdVita”). The acquisition strengthened the Group’s expertise and intellectual property rights around the inhaled formulation and delivery of Aviptadil.

The Group maintained an internal marketing and sales infrastructure in Switzerland, the U.S., Italy, and Germany, dedicated to the direct commercialization of PKU GOLIKE®. For the commercialization of its other commercially available products, as well as PKU GOLIKE outside of these key markets, the Group entered into licensing or distribution agreements with third parties. In December 2023, the Group initiated a progressive transition from its direct marketing and sales infrastructure to a partnership-based model for PKU GOLIKE.

These unaudited condensed consolidated interim financial statements were approved for publication by the Company’s Board of Directors on August 29, 2024.

2. New and revised International Financial Reporting Standards (IFRS)

There were no new standards or amendments to existing standards that have a significant impact on the Group’s accounting policies and these interim financial statements.

3. Summary of significant accounting policies

3.1 Basis of preparation

These condensed consolidated interim financial statements were prepared in accordance with IAS 34 ‘Interim Financial Reporting’ as issued by the International Accounting Standards Board (IASB). They do not include all disclosures that would otherwise be required in a complete set of financial statements and should therefore be read in conjunction with the Group’s annual consolidated financial statements for the year ended December 31, 2023. They have been prepared under the historical cost convention, as modified by the revaluation of financial instruments at fair value and are presented in Swiss francs (CHF). All values are rounded to the nearest thousand (TCHF), except when otherwise indicated.

3.2 Significant accounting policies

The accounting policies used in the preparation and presentation of the condensed interim consolidated financial statements are consistent with those applied for the Group’s annual consolidated financial statements for the year ended December 31, 2023.

Certain comparative figures have been reclassified to conform with the current period’s presentation.

 

- 6 -


3.3 Interim measurement note

The business is not subject to any seasonality. Expenses largely depend on the phase of the respective projects, particularly with regard to external research and development expenditures.

Costs that incur unevenly during the financial year are anticipated or deferred in the interim report only if it would also be appropriate to anticipate or defer such costs at the end of the financial year.

4. Summary of critical accounting judgments and key sources of estimation uncertainty

The preparation of the consolidated financial statements in conformity with IFRS requires management to make estimates and assumptions that affect the application of policies and reported amounts of assets, liabilities, income, expenses and related disclosures. The estimates and underlying assumptions are based on historical experience and various other factors that are believed to be reasonable under the circumstances, the results of which form the basis for making judgments about carrying values of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates.

The critical judgments in applying accounting policies and the key sources of estimation uncertainty are consistent with those used in the consolidated financial statements for the year ended December 31, 2023, with the following amendments:

License and Supply Agreement with Eton Pharmaceuticals, Inc.

On March 21, 2024, the Company entered into a License and Supply Agreement (“LSA”) granting Eton Pharmaceuticals, Inc. (“Eton”) the exclusive rights to commercialize the GOLIKE family of products in the United States. Under the terms of the agreement, the Company received an upfront payment of USD 2.2 million (CHF 2.0 million) and is eligible to receive up to USD 2.0 million (CHF 1.8 million) in additional sales milestones, as well as variable mid-teens royalties on net sales.

Revenue from this transaction is recognized in accordance with IFRS 15, based on the substance of the agreement. Management has applied its judgment to determine performance obligations, transaction prices, and the completion of performance obligations over time. The following distinct performance obligations were identified in the Eton LSA: (i) delivery of an exclusive license for the commercialization of existing GOLIKE products, (ii) delivery of an exclusive license for the commercialization of certain GOLIKE product line extensions under development, and (iii) commitment to manufacture and supply the GOLIKE products for a specified duration.

The transaction price was allocated based on the estimated stand-alone selling price of each performance obligation. Of the CHF 2.0 million non-refundable upfront payment received from Eton, CHF 1.6 million was allocated to the first performance obligation and recognized as revenue upon execution of the LSA, as the license constitutes functional intellectual property transferred on that date. The remaining CHF 0.4 million was allocated to the second performance obligation and will be recognized as revenue upon completion of development. The allocation of the transaction proceeds was estimated based on a discounted cash flow approach, considering several factors, including estimated sales, manufacturing costs, development timelines, and probabilities of success.

In accordance with the sales-based royalties exception, royalties and milestone payments are recognized when the corresponding sales occur, to the extent the Company is entitled to such revenue. Revenue derived from manufacturing and supply is recognized upon delivery of products, as control of the products transfers at that point.

For the six-month period ended June 30, 2024, the Company recognized CHF 1.6 million as license revenue under the Eton LSA, in addition to accrued royalties and product sales for supply to Eton. As of June 30, 2024, CHF 0.4 million was recorded as deferred income on the consolidated balance sheet for the performance obligations that were not yet completed.

Issuance of warrants to GEM

As described in note 13, the Company extinguished an outstanding liability of TCHF 1,368 by issuing warrants to purchase the Company’s ordinary shares at a predetermined price. The issuance of the warrants has been accounted for as consideration paid for the extinguishment of the liability. The fair value of the warrants, determined using the Black-Scholes valuation model, closely approximated the carrying amount of the liability. Consequently, no gain or loss was recognized on the extinguishment of the liability. The fair value of the warrants issued was credited to equity.

Going concern

These consolidated financial statements have been prepared assuming the Group will continue as a going concern which contemplates the continuity of operations, realization of assets and the satisfaction of liabilities in the ordinary course of business.

As of August 30, 2024, the Group had cash and cash equivalents of CHF 15.1 million. Based on financial projections and available cash, the Group is expected to have sufficient resources to fund operations for at least the next twelve months.

 

- 7 -


Since its inception, the Group has primarily relied on external financing to fund its cash needs and has experienced recurring losses. The Group may continue to generate operating losses in the foreseeable future. The Group’s long-term viability depends on its ability to raise additional capital or to generate positive cash flows to support its operations. The Group may never achieve sustainable profitability and is exposed to all the risks inherent in establishing a business. Management intends to continue to explore options to obtain additional funding. However, there can be no assurance that capital will be available in sufficient amounts or on acceptable terms. If Relief is unable to obtain the required funding, it will be forced to delay, reduce or eliminate some or all of its research and development programs, which could adversely affect its business prospects or result in the Group’s inability to continue operations.

5. Segment information

5.1 Information on revenue

The disaggregation of the Group’s revenue is presented in the following table:

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Revenue streams

     

Royalties

     832        812  

Product sales

     2,668        2,042  

Licensing fees

     1,675        —   

Revenue from research and development services

     406        169  
  

 

 

    

 

 

 

Total revenue

     5,581        3,023  
  

 

 

    

 

 

 

Geographical area

     

Switzerland

     730        237  

Europe (excluding Switzerland)

     1,544        1,319  

North America

     2,541        735  

Rest of the world

     766        732  
  

 

 

    

 

 

 

Total revenue

     5,581        3,023  
  

 

 

    

 

 

 

Timing of revenue recognition

     

Point in time

     5,581        3,023  

Over time

     —         —   
  

 

 

    

 

 

 

Total revenue

     5,581        3,023  
  

 

 

    

 

 

 

Effective March 21, 2024, Relief ceased direct commercialization of PKU GOLIKE in the United States and began generating revenue from supplying PKU GOLIKE to Eton and receiving sales royalties. As detailed in note 4, the Company recognized licensing income of TCHF 1,553 in the current reporting period.

5.2 Geographical location of non-current assets

 

TCHF

   June 30, 2024      December 31, 2023  

Switzerland

     55,998        57,189  

Rest of the world

     96        193  
  

 

 

    

 

 

 

Total non-current assets *

     56,094        57,382  
  

 

 

    

 

 

 

 

*

Without financial assets and deferred tax assets

 

- 8 -


6. Intangible assets

 

TCHF

   Technologies,
patents and

trademarks
    Licenses     In-process
research and

development
    Goodwill     Total  

Historical cost

          

January 1, 2023

     39,531       13,729       132,709       8,658       194,627  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Acquisition price adjustment

     —        —        (188     —        (188

Divestment

     —        (9,747     —        (455     (10,202

December 31, 2023

     39,531       3,982       132,521       8,203       184,237  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Addition

     86       —        —        —        86  

June 30, 2024

     39,617       3,982       132,521       8,203       184,323  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Accumulated amortization and impairment

          

January 1, 2023

     (29,543     —        (529     (1,640     (31,712
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Amortization

     (1,930     (752     —        —        (2,682

Impairment

     —        —        (89,878     (6,017     (95,895

Divestment

     —        466       —        —        466  

December 31, 2023

     (31,473     (286     (90,407     (7,657     (129,823
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Amortization

     (965     (142     —        —        (1,107

June 30, 2024

     (32,438     (428     (90,407     (7,657     (130,930
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Carrying amount per class

          

December 31, 2023

     8,058       3,696       42,114       546       54,414  

June 30, 2024

     7,179       3,554       42,114       546       53,393  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Carrying amount per asset

          

PKU Golike

     4,263       —        —        —        4,263  

Diclofenac

     2,916       —        —        360       3,276  

ACER-001

     —        3,554       —        186       3,740  

RLF-100

     —        —        17,130       —        17,130  

RLF-TD011

     —        —        24,858       —        24,858  

RLF-OD032

     —        —        126       —        126  

June 30, 2024

     7,179       3,554       42,114       546       53,393  
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

PKU Golike

     4,344       —        —        —        4,344  

Diclofenac

     3,714       —        —        360       4,074  

ACER-001

     —        3,696       —        186       3,882  

RLF-100

     —        —        17,130       —        17,130  

RLF-TD011

     —        —        24,858       —        24,858  

RLF-OD032

     —        —        126       —        126  

December 31, 2023

     8,058       3,696       42,114       546       54,414  

Impairment test

Intangible assets with finite lives are amortized over their useful economic life and assessed for impairment whenever there is an indication that the intangible asset may be impaired. Intangible assets with indefinite useful lives are not amortized but are tested for impairment either individually or at the cash-generating unit level. The Group generally tests its intangible assets for impairment at the end of the year, or more frequently if events or changes in circumstances indicate that intangible assets may be impaired. As of June 30, 2024, the Group did not identify significant changes that would indicate the carrying value of its intangible assets and goodwill might exceed their respective carrying amounts. Consequently, no impairment test was conducted.

The completion of the development of in-process research and development assets is subject to the availability of capital, which is uncertain as discussed in note 4. If the Group is unable to secure sufficient capital, it will be forced to delay or abandon certain development activities, which could lead to a material impairment of the affected assets.

 

- 9 -


7. Leases

7.1 Right-of-use assets

 

TCHF

   Building      Equipment      Total  

Historical cost

        

January 1, 2023

     2,529        686        3,215  
  

 

 

    

 

 

    

 

 

 

Addition

     86        468        554  

Disposal

     (89      (46      (135

Foreign exchange difference

     (6      (2      (8

December 31, 2023

     2,520        1,106        3,626  
  

 

 

    

 

 

    

 

 

 

Addition

     —         136        136  

Disposal

     (98      (81      (179

Foreign exchange difference

     13        1        14  

June 30, 2024

     2,435        1,162        3,597  
  

 

 

    

 

 

    

 

 

 

Accumulated depreciation

        

January 1, 2023

     (436      (137      (573
  

 

 

    

 

 

    

 

 

 

Depreciation

     (285      (252      (537

Disposal

     41        11        52  

Foreign exchange difference

     1        1        2  

December 31, 2023

     (679      (377      (1,056
  

 

 

    

 

 

    

 

 

 

Depreciation

     (131      (142      (273

Disposal

     54        45        99  

Foreign exchange difference

     (4             (4

June 30, 2024

     (760      (474      (1,234
  

 

 

    

 

 

    

 

 

 

Carrying amount

        

December 31, 2023

     1,841        729        2,570  

June 30, 2024

     1,675        688        2,363  

7.2 Maturity of lease liabilities

 

TCHF

   June 30, 2024      December 31, 2023  

< 1 year

     386        524  

1-5 years

     1,891        1,824  

> 5 years

     128        262  
  

 

 

    

 

 

 

Total

     2,405        2,610  
  

 

 

    

 

 

 

7.3 Amounts recognized in profit or loss

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Lease expense for short-term and low value leases

     28        25  

Depreciation expense on right-of-use assets (note 20)

     273        220  

Interest expense on lease liabilities (note 21)

     22        13  

8. Inventories

 

TCHF

   June 30, 2024      December 31, 2023  

Raw material

     2,942        2,728  

Finished goods

     140        656  
  

 

 

    

 

 

 

Gross inventories

     3,082        3,384  

Valuation allowance

     (2,708      (2,827
  

 

 

    

 

 

 

Total

     374        557  
  

 

 

    

 

 

 

 

- 10 -


9. Other current assets

 

TCHF

   June 30, 2024      December 31, 2023  

Other receivables

     1,081        972  

Accrued revenue

     724        501  

Prepaid expenses

     668        345  

VAT receivable

     133        168  

Deposits

     4        9  

Other

     35        25  
  

 

 

    

 

 

 

Total

     2,645        2,020  
  

 

 

    

 

 

 

10. Share capital

10.1 Issued share capital

As of June 30, 2024, and December 31, 2023, the share capital consisted of 14,040,837 issued, fully paid shares, including 1,500,398 shares in treasury. In the six-month period ended June 30, 2024, the Company reduced the nominal value of its share capital from CHF 4.00 to CHF 0.10 per share. The reduction proceeds, amounting to TCHF 54,759, were allocated to the share premium reserve.

10.2 Capital band

As of June 30, 2024, the Board of Directors was authorized, at any time until 25 April 2029, to increase the share capital by the issuance of up to 7,000,000 ordinary shares with a nominal value of CHF 0.10, under the terms and conditions set forth in Article 3ater of Relief’s Articles of Association.

10.3 Conditional share capital

The conditional share capital of the Company as of June 30, 2024, was TCHF 700, consisting of 7,000,000 shares with a par value of CHF 0.10 each, of which 1,000,000 shares to be used for stock options and 6,000,000 shares for grant of option rights in connection with bonds, notes or similar financial instruments issued by the Company.

10.4 Outstanding options and warrants

As of June 30, 2024, the Company had 403,242 outstanding stock options under its stock option plans and 4,850,000 outstanding warrants. Of these warrants, 1,500,000 represent the unexercised portion of warrants issued in a private placement in June 2023, with an exercise price of CHF 3.40 per share and exercisable until June 21, 2028. The remaining 3,350,000 warrants were issued in February 2024, as described in note 13. Each option and warrant entitle the holder to acquire one share at a predetermined price, subject to certain vesting conditions where applicable.

11. Defined benefit obligations

 

TCHF

   June 30, 2024      December 31, 2023  

Present value of pension benefit obligation

     3,953        4,517  

Fair value of pension plan assets

     (3,171      (3,532
  

 

 

    

 

 

 

Net pension defined benefit obligation

     782        985  

Present value of other benefit obligations

     290        604  
  

 

 

    

 

 

 

Total defined benefit obligations

     1,072        1,589  
  

 

 

    

 

 

 

11.1 Defined benefit plan

The actuarial valuation of plan assets and the present value of the defined benefit obligation was conducted as of December 31, 2023. During the six-month period ended June 30, 2024, the Group significantly reduced the number of employees covered by the defined benefit plans. Consequently, a curtailment was recognized, resulting in a reduction of the net defined benefit obligation to TCHF 782 from TCHF 985 as of December 31, 2023.

The gain from the reduction in the present value of the net defined benefit obligation due to the curtailment, amounting to TCHF 169, has been recognized in the consolidated statement of loss under ‘Personnel expenses’ as past service cost (note 18).

11.2 Other employee benefits

The obligations for other employee benefits mainly consist of end of service indemnities, which do not have the character of pensions, and are classified as a defined benefit plan in accordance with IAS 19.

 

- 11 -


12. Provisions

 

TCHF

   Contingent
consideration (i)
     Legal and
regulatory (ii)
     Other (iii)      Total  

Balance at December 31, 2023

     6,203        —         235        6,438  

Unwinding of discount on provisions

     155        —         —         155  

Variation due to assumption adjustment

     —         —         —         —   

Foreign exchange difference

     107        —         —         107  

Utilization

     —         —         (216      (216

Unused amounts reversed

     —         —         (19      (19
  

 

 

    

 

 

    

 

 

    

 

 

 

Balance at June 30, 2024

     6,465                      6,465  
  

 

 

    

 

 

    

 

 

    

 

 

 

(i) Contingent consideration for business acquisitions

As of June 30, 2024, the Group recognized provisions of TCHF 6,465 for contingent payments that may become due to the former shareholders of APR and AdVita upon completion of pre-agreed milestones.

(ii) Legal and regulatory proceedings

In the ordinary course of business, the Group is subject to potential liabilities arising from litigations and other disputes. As of June 30, 2024, there was no litigation considered to have a reasonably possible or probable impact that could result in a material loss to the Group.

(iii) Other

As of December 31, 2023, the Group had constituted provisions totaling TCHF 235 for remaining termination costs anticipated in connection with the transition from a direct marketing and sales infrastructure to a partnership-based model. As of June 30, 2024, the Group did not expect any additional material costs related to this transition.

13. Financial liabilities due to related parties

In January 2021, the Company signed a financing agreement with its largest shareholder, GEM Global Yield LLC SCS and GEM Yield Bahamas Limited (“GEM”), for the implementation of a share subscription facility (the “SSF”) in the amount of up to CHF 50 million until January 20, 2024. The Company agreed to pay GEM a commitment fee (the “Fee”) of TCHF 1,250 plus accrued interest. The Fee was payable on demand and bore interest at 1% above the base rate of Barclays Bank plc. As the obligation to pay the Fee arose with the execution of the agreement, the Company recorded it in full as a liability on the signature date. The corresponding expense was recognized as financial expense (note 21) over the SSF commitment period of three years ended January 20, 2024.

In February 2024, the Company renewed the SSF agreement with GEM for an additional three-year period ending January 20, 2027. As part of the renewal agreement, GEM agreed to forgive an outstanding liability of TCHF 1,368, constituted by the Fee and accrued interests as of the renewal date. In consideration of GEM’s capital commitment and this debt waiver, Relief issued GEM warrants to purchase up to 3,350,000 ordinary shares at a price of CHF 1.70 per share, exercisable from the issuance date, and expiring on January 20, 2027.

As of June 30, 2024, the Company had not drawn on the SSF.

14. Other current payables and liabilities

 

TCHF

   June 30, 2024      December 31, 2023  

Accrued expenses

     1,587        1,736  

Personnel-related accruals and payables

     857        1,049  

Deferred revenue

     426        114  

Other current liabilities

     204        534  
  

 

 

    

 

 

 

Total

     3,074        3,433  
  

 

 

    

 

 

 

 

- 12 -


15. Other gains

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Income from sublease agreements

     51        50  

Other

     22        16  
  

 

 

    

 

 

 

Total other gains

     73        66  
  

 

 

    

 

 

 

16. Cost of sales

Expenses incurred with third parties in relation to the purchase and manufacturing of drug products for sale, as well as laboratory supplies in connection with research and development services provided to customers, are classified in ‘raw materials and consumables expenses’. Expenses incurred with third parties in relation to advertising, marketing, sales promotion, shipping, distribution and commission on sales, are classified as ‘external selling and distribution expenses’.

The increase in ‘raw materials and consumables expenses’ correlates with the increase in revenue from product sales and contract services. A change in the product mix, with a lower proportion of sales stemming from higher-margin products, increased the ratio of raw materials and consumables expenses over product sales and contract services revenue.

External selling and distribution expenses decreased mainly due to scaled-back marketing activities for PKU GOLIKE following the Company’s decision to transition its commercial business model.

17. External research and development expenses

External research and development expenses include costs associated with outsourced clinical research organization activities, sponsored research studies, clinical trial costs, process development, and product manufacturing expenses in relation to research and development programs.

During the six-month period ended June 30, 2024, external research and development expenses primarily consisted of costs associated with the clinical and drug product development of RLF-OD032 and RLF-TD011.

18. Personnel expenses

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Salaries and social security expense

     3,579        5,735  

Share-based payment expense

     225        511  

Past service cost for pension obligations

     (169      —   

Service cost for other benefit obligations

     (151      13  
  

 

 

    

 

 

 

Total personnel expenses

     3,484        6,259  
  

 

 

    

 

 

 

During the six-month period ended June 30, 2024, the Company scaled back its commercial operations, which included a phased reduction in its sales and marketing workforce. Additionally, the Company undertook further reductions in its management and administrative personnel. As of June 30, 2024, Relief employed 36 full-time equivalents, a decrease from 49 full-time equivalents as of December 31, 2023.

These measures have resulted in a significant decrease in personnel expenses and a reduction in post-employment benefit obligations (note 11). The full financial impact of these reductions is expected to be realized in the second half of 2024.

19. Other administrative expenses

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Professional services

     1,059        1,947  

Other administrative expenses

     958        1,515  
  

 

 

    

 

 

 

Total other administrative expenses

     2,017        3,462  
  

 

 

    

 

 

 

The decrease in administrative expenses is primarily attributable to the Company’s efforts to streamline its expense base and the completion of certain non-recurring corporate projects from the comparative period.

 

- 13 -


20. Amortization and depreciation expense

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Amortization of intangible assets (note 6)

     1,107        1,456  

Depreciation of rights-of-use assets (note 7)

     273        220  

Depreciation of property and equipment

     58        28  
  

 

 

    

 

 

 

Total amortization and depreciation expense

     1,438        1,704  
  

 

 

    

 

 

 

21. Financial income and expense

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Interest income on cash deposits

     79        —   

Interest income on deferred payments

     43        —   

Foreign exchange gain, net

     78        —   
  

 

 

    

 

 

 

Total financial income

     200        —   
  

 

 

    

 

 

 

Unwinding of discount on provisions (note 12)

     155        171  

SSF commitment fee (note 13)

     23        207  

Interest expense related to leases

     22        13  

Bank charges

     6        17  

Foreign exchange loss, net

     —         323  

Other financial expenses

     13        59  
  

 

 

    

 

 

 

Total financial expense

     219        790  
  

 

 

    

 

 

 

22. Income taxes

 

TCHF

   01.01.-30.06.2024      01.01.-30.06.2023  

Current tax expense for the year

     —         —   

Deferred tax income recognized in the year

     29        7,643  

Write-down of deferred tax assets

     (589      —   
  

 

 

    

 

 

 

Net income tax (expense)/gain

     (560      7,643  
  

 

 

    

 

 

 

In the current reporting period, income tax expenses primarily resulted from the write-down of deferred tax assets related to a foreign subsidiary. The winding down of this subsidiary’s operations was part of the Group’s strategic shift in its commercial activities.

In the six-month period ended June 30, 2023, the Company recognized an income tax gain primarily related to the amortization and impairment of intangible assets, which resulted in a corresponding reduction in the temporary difference between the carrying amount of these assets and their tax base.

23. Earnings per share

 

     01.01.-30.06.2024      01.01.-30.06.2023  

Loss attributable to shareholders (in TCHF)

     (4,557      (56,499

Weighted average number of shares

     12,540,439        11,082,004  
  

 

 

    

 

 

 

Total basic and diluted loss per share (in CHF)

     (0.363      (5.098
  

 

 

    

 

 

 

Basic and diluted results per share are calculated by dividing the net result attributable to the shareholders of the Group’s parent company by the weighted average of shares outstanding during the period.

Neither outstanding options and warrants nor effects from the contingent liabilities payable in shares have been considered in the diluted loss calculation as their effect is anti-dilutive.

 

- 14 -


24. Related party transactions

24.1 Related party transactions

During the six-month period ended June 30, 2024, the Company did not engage in any related party transactions, except for compensation provided to its management and the renewal of its SSF agreement with GEM (note 13).

24.2 Related party balances

As of June 30, 2024, the Company had no outstanding balances payable to or receivable from related parties.

25. Contingent liabilities

25.1 Business combinations with APR and AdVita

The acquisition agreements for APR and AdVita provide for remaining contingent payment obligations in the aggregate maximum amounts of CHF 28 million and EUR 10 million (CHF 9.6 million), respectively, payable upon achievement of pre-agreed objectives. As of June 30, 2024, a provision totaling CHF 6.5 million (December 31, 2023: CHF 6.2 million) was recognized to account for the probability-weighted present value at the balance sheet date of these possible future payments (note 12).

25.2 Acquisition of RLF-OD032

Pursuant to the agreement concluded with Meta Healthcare Ltd. for the acquisition of RLF-OD032 in July 2022, Relief may issue additional payments of approximately TCHF 250 contingent on pre-specified development milestones. Relief committed to paying Meta Healthcare Ltd. royalties on possible future net commercialization profit from RLF-OD032 of a low double-digit percentage.

25.3 License agreement with Acer

Pursuant to the license agreement concluded with Acer in August 2023, Relief shall pay Acer a variable, continuing royalty up to a maximum of 10% of potential future net sales of OLPRUVA® in Europe and 20% of any value received by Relief from sublicensing transactions relating to OLPRUVA®.

25.4 Settlement agreement with NRx Pharmaceuticals

Pursuant to the settlement and asset purchase agreements concluded with NRx Pharmaceuticals, Inc. (“NRx”) in November 2022, Relief committed to paying NRx up to USD 13 million (CHF 11.7 million) in aggregate as milestone payments upon marketing approval of an Aviptadil product. Additionally, Relief has agreed to pay single-digit percentage royalties on potential future sales of an Aviptadil product, up to a maximum of USD 30 million (CHF 27.0 million) in aggregate.

26. Events after the reporting period

Sale of royalty interests to SWK

On August 2, 2024, the Company entered into a definitive agreement with SWK Funding LLC (“SWK”) for the sale of royalty interests in OLPRUVA®, GOLIKE® and CAMBIA®. Relief received USD 5.75 million (CHF 5 million) from SWK and may receive an additional USD 5.25 million (CHF 4.6 million) contingent on the achievement of near-term milestones.

Under the terms of the agreement, SWK acquired all future OLPRUVA royalties from Relief’s August 2023 agreement with Acer and all future royalties and milestone payments from the March 2024 license agreement with Eton. SWK will return to Relief 80% of OLPRUVA royalties exceeding USD 2.25 million annually and all royalties exceeding USD 4.5 million. For GOLIKE, SWK will return 80% of GOLIKE royalties exceeding USD 1.32 million annually and all royalties exceeding USD 1.98 million. Additionally, SWK acquired all future royalties from CAMBIA, which represented CHF 0.17 million in net royalty income in the six-month period ended June 30, 2024.

The agreement will terminate, and all royalties will revert to Relief once SWK has received 2.75 times its invested capital.

There were no other material events after the balance sheet date that would require adjustment to these consolidated financial statements or disclosure under this heading.

 

- 15 -