Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Operating activities
Net loss	$ (98,771)	$ (27,945)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation	1,133	639
Loss on disposal of property and equipment	94	0
Stock-based compensation	9,231	1,060
Change in fair value of convertible promissory notes	35,199	0
Change in fair value of warrant liability	2,180	198
Amortization of premium on short -term investments	1,865	83
Accretion of debt issuance costs	279	234
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(6,851)	(391)
Other noncurrent assets	(1,048)	0
Accounts payable	1,854	(148)
Accrued expenses	2,686	1,132
Other current liabilities	(176)	240
Other noncurrent liabilities	624	25
Net cash used in operating activities	(51,701)	(24,873)
Investing activities
Purchases of short-term investments	(195,684)	(6,077)
Sales of short-term investments	33,688	20,616
Maturities of shot-term investments	35,999	10,846
Purchases of property and equipment	(4,864)	(1,380)
Net cash (used in) provided by investing activities	(130,861)	24,005
Financing activities
Proceeds from initial public offering, net of issuance costs	237,199	0
Proceeds from issuance of common stock, net of repurchases	3,577	45
Proceeds from issuance under employee stock purchase program	752	0
Proceeds from issuance of convertible promisorry notes	130,500	0
Proceeds from issuance of debt	10,500	7,500
Repayments of debt principal and issuance costs in connection with refinancing	(10,400)	0
Issuance costs in connection with Series B convertible preferred stock	0	(30)
Net cash provided by financing activities	372,128	7,515
Increase in cash and cash equivalents and restricted cash	189,566	6,647
Cash and cash equivalents and restricted cash, beginning of year	12,170	5,523
Cash and cash equivalents and restricted cash, end of period	201,736	12,170
Supplemental disclosure for cash activities
Interest paid	569	461
Supplemental disclosure for non-cash activities
Vesting of restricted stock	798	33
Cashless warrant exercise	300	0
Conversion of preferred stock to common stock	69,184	0
Conversion of convertible promissory notes to common stock	165,699	0
Purchase of property plant and equipment included in accounts payable	67	14
Warrants issued in connection with issuance of long-term debt		$ 189