Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Cash flows from operating activities:
Net loss	$ (114,248)	$ (173,034)
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation expense	21,962	18,348
Depreciation and amortization	564	95
Change in fair value of financial instruments	4,200	(5,520)
Change in deferred taxes	(26,380)	(83)
Changes in operating assets and liabilities:
Tax incentive receivable	(4,157)	(7,847)
Prepaid expenses and other assets	(3,211)	4,209
Operating leases, net	(1,968)	0
Accounts payable	(3,308)	3,755
Accrued expenses and other liabilities	(2,841)	11,095
Other, net	95	0
Net cash used in operating activities	(129,292)	(148,982)
Cash flows from investing activities:
Purchases of investments in marketable securities	(194,836)	0
Proceeds from redemption of investments in marketable securities	86,248	0
Purchases of property and equipment	(141)	(485)
Net cash used in investing activities	(108,729)	(485)
Cash flows from financing activities:
Proceeds from issuance of shares under ATM program, net of issuance costs	14,564	0
Proceeds from option exercises	192	629
Other, net	0	(261)
Net cash provided by financing activities	14,756	368
Effect of exchange rate on cash and cash equivalents	1,119	(1,140)
Net decrease in cash and cash equivalents	(222,146)	(150,239)
Cash and cash equivalents at beginning of period	393,644	595,082
Cash and cash equivalents at end of period	171,498	444,843
Supplemental disclosure:
Interest paid	7,336	5,074
Income taxes paid	2,947	862
Operating lease payments reducing operating lease liabilities	785	0
ROU assets obtained in exchange for operating lease liabilities	9,711	0
Non-cash investing and financing activities:
Issuance of ordinary shares to settle outstanding contingent value rights	$ 0	$ 39,680