Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Total	Ordinary Shares	Additional paid-in capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Ordinary shares, beginning balance (in shares) at Dec. 31, 2021		89,988,228
Beginning balance at Dec. 31, 2021	$ 491,554	$ 252	$ 876,267	$ 688	$ (385,653)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes (in shares)		3,938,423
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes	37,748	$ 10	37,738
Stock option exercises (in shares)		150,588
Stock option exercises	688		688
Share-based compensation expense	18,348		18,348
Vesting of ordinary shares (in shares)		494,412
Vesting of ordinary shares	0	$ 1	(1)
Foreign currency translation adjustments	(2,383)			(2,383)
Unrealized gain on available for sale securities, net of tax	0
Net loss	(173,034)				(173,034)
Ordinary shares, ending balance (in shares) at Sep. 30, 2022		94,571,651
Ending balance at Sep. 30, 2022	372,921	$ 263	933,040	(1,695)	(558,687)
Ordinary shares, beginning balance (in shares) at Jun. 30, 2022		94,271,917
Beginning balance at Jun. 30, 2022	420,039	$ 263	925,730	(1,142)	(504,812)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock option exercises (in shares)		72,834
Stock option exercises	283		283
Share-based compensation expense	7,027		7,027
Vesting of ordinary shares (in shares)		226,900
Foreign currency translation adjustments	(553)			(553)
Unrealized gain on available for sale securities, net of tax	0
Net loss	(53,875)				(53,875)
Ordinary shares, ending balance (in shares) at Sep. 30, 2022		94,571,651
Ending balance at Sep. 30, 2022	$ 372,921	$ 263	933,040	(1,695)	(558,687)
Ordinary shares, beginning balance (in shares) at Dec. 31, 2022	94,843,391	94,843,391
Beginning balance at Dec. 31, 2022	$ 336,169	$ 265	939,261	(1,497)	(601,860)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes (in shares)		2,040,816
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes	$ 14,564	$ 5	14,559
Stock option exercises (in shares)	44,770	44,770
Stock option exercises	$ 192		192
Share-based compensation expense	21,962		21,962
Vesting of ordinary shares (in shares)		908,463
Vesting of ordinary shares	0	$ 1	(1)
Shares withheld to pay employee withholding tax on share-based compensation (in shares)		(269,957)
Shares withheld to pay employee withholding tax on share-based compensation	(1,525)		(1,525)
Foreign currency translation adjustments	1,241			1,241
Unrealized gain on available for sale securities, net of tax	1,035			1,035
Net loss	$ (114,248)				(114,248)
Ordinary shares, ending balance (in shares) at Sep. 30, 2023	97,567,483	97,567,483
Ending balance at Sep. 30, 2023	$ 259,390	$ 271	974,448	779	(716,108)
Ordinary shares, beginning balance (in shares) at Jun. 30, 2023		95,299,673
Beginning balance at Jun. 30, 2023	276,606	$ 266	952,854	946	(677,460)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes (in shares)		2,040,816
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes	14,564	$ 5	14,559
Stock option exercises (in shares)		40,994
Stock option exercises	177		177
Share-based compensation expense	7,559		7,559
Vesting of ordinary shares (in shares)		291,734
Shares withheld to pay employee withholding tax on share-based compensation (in shares)		(105,734)
Shares withheld to pay employee withholding tax on share-based compensation	(701)		(701)
Foreign currency translation adjustments	(419)			(419)
Unrealized gain on available for sale securities, net of tax	252			252
Net loss	$ (38,648)				(38,648)
Ordinary shares, ending balance (in shares) at Sep. 30, 2023	97,567,483	97,567,483
Ending balance at Sep. 30, 2023	$ 259,390	$ 271	$ 974,448	$ 779	$ (716,108)