Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 171,498	$ 393,644
Short-term investments	109,843	0
Tax incentive receivable	28,459	24,166
Prepaid expenses and other current assets	22,653	19,937
Total current assets	332,453	437,747
Property and equipment, net	1,102	1,168
Operating lease right-of-use assets	12,130	0
Deferred tax asset	29,577	3,512
Other, net	2,102	1,880
Total assets	377,364	444,307
Current liabilities:
Accounts payable	10,848	13,836
Accrued expenses and other current liabilities	24,106	24,502
Total current liabilities	34,954	38,338
Long term debt	74,000	69,800
Operating lease liabilities	9,020	0
Total liabilities	117,974	108,138
Commitments and contingencies (Note 6)
Shareholders’ equity:
Ordinary shares: £0.002 nominal value: 152,500,000 shares authorized, 97,567,483 issued and outstanding at September 30, 2023: 152,500,000 shares authorized, 94,843,391 issued and outstanding at December 31, 2022	271	265
Additional paid-in capital	974,448	939,261
Accumulated other comprehensive loss	779	(1,497)
Accumulated deficit	(716,108)	(601,860)
Total shareholders’ equity	259,390	336,169
Total liabilities and shareholders' equity	$ 377,364	$ 444,307