Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Total	Ordinary Shares	Additional paid-in capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Ordinary shares, beginning balance (in shares) at Dec. 31, 2021		89,988,228
Beginning balance at Dec. 31, 2021	$ 491,554	$ 252	$ 876,267	$ 688	$ (385,653)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes (in shares)		3,938,423
Issuance of ordinary shares to settle outstanding contingent value rights, net of employee withholding taxes	37,748	$ 10	37,738
Stock option exercises (in shares)		59,541
Stock option exercises	335		335
Share-based compensation expense	5,718		5,718
Vesting of ordinary shares (in shares)		35,776
Foreign currency translation adjustments	(706)			(706)
Net loss	(54,498)				(54,498)
Ordinary shares, ending balance (in shares) at Mar. 31, 2022		94,021,968
Ending balance at Mar. 31, 2022	$ 480,151	$ 262	920,058	(18)	(440,151)
Ordinary shares, beginning balance (in shares) at Dec. 31, 2022	94,843,391	94,843,391
Beginning balance at Dec. 31, 2022	$ 336,169	$ 265	939,261	(1,497)	(601,860)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock option exercises (in shares)	0
Share-based compensation expense	$ 7,190		7,190
Vesting of ordinary shares (in shares)		332,292
Vesting of ordinary shares	0	$ 1	(1)
Shares withheld to pay employee withholding tax on share-based compensation (in shares)		(72,436)
Shares withheld to pay employee withholding tax on share-based compensation	(282)		(282)
Foreign currency translation adjustments	898			898
Net loss	$ (50,714)				(50,714)
Ordinary shares, ending balance (in shares) at Mar. 31, 2023	95,103,247	95,103,247
Ending balance at Mar. 31, 2023	$ 293,261	$ 266	$ 946,168	$ (599)	$ (652,574)