Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Operating expenses:
Research and development	$ 32,826	$ 36,853
General and administrative	16,051	14,385
Change in fair value of contingent value rights	0	1,980
Loss from operations	(48,877)	(53,218)
Interest income	2,531	104
Interest expense	(2,345)	(1,500)
Other (expense) income, net	(1,346)	196
Loss before income taxes	(50,037)	(54,418)
Income tax expense	677	80
Net loss	(50,714)	(54,498)
Other comprehensive income (loss):
Foreign currency translation adjustments	898	(706)
Total comprehensive loss	$ (49,816)	$ (55,204)
Net loss per ordinary share - basic (in dollars per share)	$ (0.53)	$ (0.60)
Net loss per ordinary share - diluted (in dollars per share)	$ (0.53)	$ (0.60)
Weighted average ordinary shares outstanding - basic (in shares)	94,937,904	90,505,345
Weighted average ordinary shares outstanding - diluted (in shares)	94,937,904	90,505,345