Commitments and Contingencies - Narrative (Details)	3 Months Ended	12 Months Ended
	Mar. 31, 2023 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Feb. 07, 2022 USD ($) ft² option
Lessee, Lease, Description [Line Items]
Purchase obligation	$ 42,000,000
Purchase obligation, to be paid, within one year	35,800,000
Purchase obligation, to be paid, over one to four years	6,200,000
Lease term				10 years
Area of real estate property | ft²				18,922
Rent expense	0
Letter of credit outstanding				$ 700,000
Number of options to extend | option				1
Lease, renewal term				5 years
Operating lease, right-of-use asset	12,271,000		$ 0
Operating lease liabilities	9,711,000			$ 9,700,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Lessee, Lease, Description [Line Items]
Maximum aggregate development and regulatory milestone payments	0
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Orexia
Lessee, Lease, Description [Line Items]
Maximum aggregate development milestone payments	44,600,000
Maximum aggregate commercial milestone payments	$ 42,000,000
Forecast
Lessee, Lease, Description [Line Items]
Rent expense		$ 1,600,000
Rent expense, year 10		$ 1,900,000