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Organization and Description of Business (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2023
Jan. 27, 2023
Dec. 31, 2022
Jul. 12, 2022
Subsidiary, Sale of Stock [Line Items]        
Accumulated deficit $ 652,574   $ 601,860  
Cash and cash equivalents and short-term investments $ 346,200      
Sufficient funding term (at least) 12 months      
At-the-market        
Subsidiary, Sale of Stock [Line Items]        
Sale of stock, consideration receivable (up to)   $ 125,000   $ 350,000