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Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Total
IPO
Over-Allotment Option
Preferred Stock
Series A Preferred
Ordinary Shares
Ordinary Shares
IPO
Ordinary Shares
Over-Allotment Option
Additional paid-in capital
Additional paid-in capital
IPO
Additional paid-in capital
Over-Allotment Option
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Beginning balance (in shares) at Jan. 29, 2021       0 7,500,000              
Beginning balance at Jan. 29, 2021 $ (4,651)     $ 0 $ 21     $ 0     $ (90) $ (4,582)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Shares issued (in shares)       22,272,721   16,500,000 2,475,000          
Shares issued 241,597 $ 298,077 $ 46,059 $ 241,597   $ 47 $ 7   $ 298,030 $ 46,052    
Issuance of Series A convertible preferred shares upon conversion of debt (in shares)       568,181                
Issuance of Series A convertible preferred shares upon conversion of debt 6,250     $ 6,250                
Acquisition of Centessa Subsidiaries (in shares)         44,758,079              
Acquisition of Centessa Subsidiaries 262,698       $ 123     262,575        
Forgiveness of convertible term loan 6,199             6,199        
Repurchase of ordinary shares concurrent with acquisition of Centessa Subsidiaries (in shares)         (4,450,000)              
Repurchase of ordinary shares concurrent with acquisition of Centessa Subsidiaries (12)       $ (12)              
Conversion of Series A convertible preferred shares into ordinary shares (in shares)       (22,840,902) 22,840,902              
Conversion of Series A convertible preferred shares into ordinary shares 0     $ (247,847) $ 65     247,782        
Stock option exercises (in shares)         50,000              
Stock option exercises 292             292        
Vesting of ordinary shares (in shares)         226,444              
Vesting of ordinary shares 0       $ 1     (1)        
Share-based compensation expense 10,093             10,093        
Foreign currency translation adjustment 2,828                   2,828  
Net loss (320,297)                     (320,297)
Ending balance (in shares) at Sep. 30, 2021       0 89,900,425              
Ending balance at Sep. 30, 2021 549,133     $ 0 $ 252     871,022     2,738 (324,879)
Beginning balance (in shares) at Jun. 30, 2021         89,899,419              
Beginning balance at Jun. 30, 2021 585,642       $ 252     866,889     3,225 (284,724)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Vesting of ordinary shares (in shares)         1,006              
Share-based compensation expense 4,133             4,133        
Foreign currency translation adjustment (487)                   (487)  
Net loss (40,155)                     (40,155)
Ending balance (in shares) at Sep. 30, 2021       0 89,900,425              
Ending balance at Sep. 30, 2021 549,133     $ 0 $ 252     871,022     2,738 (324,879)
Beginning balance (in shares) at Dec. 31, 2021         89,988,228              
Beginning balance at Dec. 31, 2021 491,554       $ 252     876,267     688 (385,653)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Shares issued (in shares)         3,938,423              
Shares issued $ 37,748       $ 10     37,738        
Stock option exercises (in shares) 150,588       150,588              
Stock option exercises $ 688             688        
Vesting of ordinary shares (in shares)         494,412              
Vesting of ordinary shares 0       $ 1     (1)        
Share-based compensation expense 18,348             18,348        
Foreign currency translation adjustment (2,383)                   (2,383)  
Net loss (173,034)                     (173,034)
Ending balance (in shares) at Sep. 30, 2022         94,571,651              
Ending balance at Sep. 30, 2022 372,921       $ 263     933,040     (1,695) (558,687)
Beginning balance (in shares) at Jun. 30, 2022         94,271,917              
Beginning balance at Jun. 30, 2022 420,039       $ 263     925,730     (1,142) (504,812)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Stock option exercises (in shares)         72,834              
Stock option exercises 283             283        
Vesting of ordinary shares (in shares)         226,900              
Share-based compensation expense 7,027             7,027        
Foreign currency translation adjustment (553)                   (553)  
Net loss (53,875)                     (53,875)
Ending balance (in shares) at Sep. 30, 2022         94,571,651              
Ending balance at Sep. 30, 2022 $ 372,921       $ 263     $ 933,040     $ (1,695) $ (558,687)