Organization and Description of Business (Details) $ / shares in Units, $ in Thousands	1 Months Ended	9 Months Ended
	Jun. 30, 2021 USD ($) shares	Sep. 30, 2022 USD ($)	Sep. 30, 2022 £ / shares	Dec. 31, 2021 USD ($)	Dec. 31, 2021 £ / shares	Jun. 30, 2021 £ / shares shares	Jun. 30, 2021 $ / shares shares
Subsidiary, Sale of Stock [Line Items]
Number of ordinary shares per American Depositary Shares (ADSs) (in shares) | shares						1	1
Common stock, nominal value (in pound sterling per share) | £ / shares			£ 0.002		£ 0.002	£ 0.002
Aggregate net proceeds in connection with the IPO and subsequent exercise of the underwriter's options | $	$ 344,100
Accumulated deficit | $		$ (558,687)		$ (385,653)
Cash and cash equivalents | $		$ 444,843		$ 595,082
Sufficient funding term (at least)		12 months
IPO
Subsidiary, Sale of Stock [Line Items]
Shares sold in offering (in shares) | shares	16,500,000
Share price (in dollars per share) | $ / shares							$ 20.00
Over-Allotment Option
Subsidiary, Sale of Stock [Line Items]
Shares sold in offering (in shares) | shares	2,475,000
Share price (in dollars per share) | $ / shares							$ 20.00