Licensing Arrangements (Details) £ in Millions	11 Months Ended
	Dec. 31, 2021 USD ($) $ / £	Dec. 31, 2021 GBP (£) $ / £	Oct. 31, 2021 USD ($)	Mar. 31, 2019 USD ($) $ / £	Mar. 31, 2019 GBP (£) $ / £	Jul. 31, 2017 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Foreign currency exchange rate, translation | $ / £	0.74	0.74		0.88	0.88
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum aggregate development and commercial milestone payments	$ 0
Collaborative arrangement, research and development expense	1,700,000
Maximum aggregate development and regulatory milestone payments	2,500,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Palladio
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum contingent consideration payment	32,500,000
Maximum aggregate commercial milestone payments	16,300,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Palladio | Pfizer
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalty payments	19,000,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Pega-One | Roche
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, research and development expense	1,000,000
Maximum aggregate commercial milestone payments	100,000,000
Maximum aggregate development and regulatory milestone payments	40,000,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Orexia | Heptares
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum aggregate development and regulatory milestone payments	33,400,000	£ 24.7
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Orexia | X-Chem
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum aggregate commercial milestone payments	5,000,000
Maximum aggregate development and regulatory milestone payments	3,000,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Orexia | Schrodinger
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, research and development expense	700,000
Maximum aggregate commercial milestone payments			$ 80,000,000
Maximum aggregate development and regulatory milestone payments			$ 35,000,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Orexia | OptiNose
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum aggregate commercial milestone payments	37,000,000
Maximum aggregate development and regulatory milestone payments	$ 8,000,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | PearlRiver Bio GmbH | LDC
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum aggregate commercial milestone payments				$ 28,400,000	£ 25.0
Maximum aggregate development and regulatory milestone payments				$ 39,500,000	£ 34.8
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Janpix Limited | Governing Council of UT
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum aggregate commercial milestone payments						$ 15,000,000
Maximum aggregate development and regulatory milestone payments						$ 15,000,000