<SEC-DOCUMENT>0001193125-24-080825-index.html : 20240328
<SEC-HEADER>0001193125-24-080825.hdr.sgml : 20240328
<ACCEPTANCE-DATETIME>20240328170145
ACCESSION NUMBER:		0001193125-24-080825
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20240328
DATE AS OF CHANGE:		20240328
EFFECTIVENESS DATE:		20240328

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Centessa Pharmaceuticals plc
		CENTRAL INDEX KEY:			0001847903
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-278341
		FILM NUMBER:		24800149

	BUSINESS ADDRESS:	
		STREET 1:		3RD FLOOR
		STREET 2:		1 ASHLEY ROAD
		CITY:			ALTRINCHAM, CHESHIRE
		STATE:			X0
		ZIP:			WA14 2DT
		BUSINESS PHONE:		44 7391 789784

	MAIL ADDRESS:	
		STREET 1:		3RD FLOOR
		STREET 2:		1 ASHLEY ROAD
		CITY:			ALTRINCHAM, CHESHIRE
		STATE:			X0
		ZIP:			WA14 2DT

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Centessa Pharmaceuticals Ltd
		DATE OF NAME CHANGE:	20210224
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>d794530ds8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: d794530ds8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>d794530dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: d794530dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>d794530dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: d794530dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>d794530dexfilingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 4 - file: d794530dexfilingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>g794530g0326005912874.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: g794530g0326005912874.jpg

</DOCUMENT>
</SEC-DOCUMENT>