<SEC-DOCUMENT>0001193125-21-188878-index.html : 20210611
<SEC-HEADER>0001193125-21-188878.hdr.sgml : 20210611
<ACCEPTANCE-DATETIME>20210611161600
ACCESSION NUMBER:		0001193125-21-188878
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20210611
DATE AS OF CHANGE:		20210611
EFFECTIVENESS DATE:		20210611

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Centessa Pharmaceuticals plc
		CENTRAL INDEX KEY:			0001847903
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-257027
		FILM NUMBER:		211011465

	BUSINESS ADDRESS:	
		STREET 1:		THE DOROTHY HODGKIN BUILDING
		STREET 2:		BABRAHAM RESEARCH CAMPUS
		CITY:			BABRAHAM, CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3FH
		BUSINESS PHONE:		44 (0)7767 003904

	MAIL ADDRESS:	
		STREET 1:		THE DOROTHY HODGKIN BUILDING
		STREET 2:		BABRAHAM RESEARCH CAMPUS
		CITY:			BABRAHAM, CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3FH

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Centessa Pharmaceuticals Ltd
		DATE OF NAME CHANGE:	20210224
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>d148316ds8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: d148316ds8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>d148316dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: d148316dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>d148316dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: d148316dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>d148316dex232.htm
<DESCRIPTION>EX-23.2
<TEXT>
Document 4 - file: d148316dex232.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.3
<SEQUENCE>5
<FILENAME>d148316dex233.htm
<DESCRIPTION>EX-23.3
<TEXT>
Document 5 - file: d148316dex233.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>g148316dsp1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: g148316dsp1.jpg

</DOCUMENT>
</SEC-DOCUMENT>