<SEC-DOCUMENT>0001193125-21-178516-index.html : 20210601
<SEC-HEADER>0001193125-21-178516.hdr.sgml : 20210601
<ACCEPTANCE-DATETIME>20210601160758
ACCESSION NUMBER:		0001193125-21-178516
CONFORMED SUBMISSION TYPE:	424B4
PUBLIC DOCUMENT COUNT:		80
FILED AS OF DATE:		20210601
DATE AS OF CHANGE:		20210601

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Centessa Pharmaceuticals plc
		CENTRAL INDEX KEY:			0001847903
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B4
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-255393
		FILM NUMBER:		21985310

	BUSINESS ADDRESS:	
		STREET 1:		THE DOROTHY HODGKIN BUILDING
		STREET 2:		BABRAHAM RESEARCH CAMPUS
		CITY:			BABRAHAM, CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3FH
		BUSINESS PHONE:		44 (0)7767 003904

	MAIL ADDRESS:	
		STREET 1:		THE DOROTHY HODGKIN BUILDING
		STREET 2:		BABRAHAM RESEARCH CAMPUS
		CITY:			BABRAHAM, CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3FH

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Centessa Pharmaceuticals Ltd
		DATE OF NAME CHANGE:	20210224
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B4
<SEQUENCE>1
<FILENAME>d123754d424b4.htm
<DESCRIPTION>424B4
<TEXT>
Document 1 - file: d123754d424b4.htm
</DOCUMENT> <DOCUMENT> <TYPE>GRAPHIC <SEQUENCE>2 <FILENAME>g123754g00c36.jpg <DESCRIPTION>GRAPHIC <TEXT> Document 2 - file: g123754g00c36.jpg
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</DOCUMENT> </SEC-DOCUMENT>