Exhibit 23.1

Independent Registered Public Accounting Firm’s Consent

We consent to the inclusion in this Registration Statement of Avista Public Acquisition Corp. II on Amendment No. 1 to Form S-1 (Filing No. 333 -257177) of our report March 19, 2021 except for Note 2 and Note 7, as to which the date is May 12, 2021, which includes an explanatory paragraph as to the Company’s ability to continue as a going concern, with respect to our audit of the financial statements of Avista Public Acquisition Corp. II as of February 12, 2021 and for the period from February 5, 2021 (inception) through February 12, 2021, which report appears in the Prospectus, which is part of this Registration Statement. We also consent to the reference to our Firm under the heading “Experts” in such Prospectus.

/s/ Marcum LLP

Marcum LLP

New York, NY

July 28, 2021