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Stockholders' Equity (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2020
Dec. 31, 2015
May 31, 2021
Cash received from options exercised under all share-based payment arrangements $ 270 $ 17      
Equity incentive, 2014 Plan          
Cash received from options exercised under all share-based payment arrangements $ 270 $ 17      
Common stock          
Number of shares issued on exercise of stock options 6,212,964 276,822      
Warrants          
Warrants to purchase shares of common stock     45,730 276,000 1,755,557
Exercise price of warrants     $ 0.53 $ 0.00001088 $ 0.01
Expenses related to issuance of warrants     $ 16 $ 18