TEXT-EXTRACT 2 filename2.txt United States securities and exchange commission logo May 17, 2024 Rajiv Shukla Chief Executive Officer Carmell Corporation 2403 Sidney Street, Suite 300 Pittsburgh, PA 15203 Re: Carmell Corporation Registration Statement on Form S-1 Filed May 10, 2024 File No. 333-279329 Dear Rajiv Shukla: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Nicholas O'Leary at 202-551-4451 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Michael A. Hedge, Esq.