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License Agreements - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended		12 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2021	Jan. 31, 2022	Jun. 30, 2020
ATAI Kures Inc. [Member] \| License Agreement Terms [Member]
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Percentage of the common stock shares outstanding					5.00%
Columbia Stock Purchase and License Agreement [Member]
License Agreements [Line Items]
Material Payment	$ 0	$ 0
Accelerate License Agreement [Member]
License Agreements [Line Items]
Material Payment	0	0
CHIBA License [Member]
License Agreements [Line Items]
Material Payment	0	0
Allergan License Agreement [Member]
License Agreements [Line Items]
Material Payment	0	0
Dalriada License Agreement [Member]
License Agreements [Line Items]
Service fees			$ 12,800
Dalriada License Agreement [Member] \| Service, Other [Member]
License Agreements [Line Items]
Service fees	0	0
Invyxis ESLA [Member]
License Agreements [Line Items]
Research and development expenses	500	$ 200
Upfront deposit				$ 1,100
Otsuka [Member] \| Otsuka Agreement [Member]
License Agreements [Line Items]
Performance obligation			$ 20,000
Otsuka [Member] \| Commercial Milestones [Member] \| Otsuka Agreement [Member]
License Agreements [Line Items]
Milestone payments, receivable	66,000
Otsuka [Member] \| Development And Regulatory Milestones [Member] \| Otsuka Agreement [Member]
License Agreements [Line Items]
Milestone payments, receivable	$ 35,000