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Notes Receivable - Additional Information (Detail)
12 Months Ended
Sep. 14, 2021
USD ($)
May 11, 2021
USD ($)
Jan. 03, 2020
USD ($)
$ / shares
Dec. 31, 2022
USD ($)
Dec. 31, 2021
€ / shares
Dec. 31, 2022
€ / shares
Dec. 31, 2022
USD ($)
$ / shares
Dec. 31, 2021
USD ($)
$ / shares
Jun. 07, 2021
€ / shares
Mar. 08, 2021
USD ($)
Notes Receivable [Line Items]                    
Convertible promissory notes issued             $ 15,000,000      
Short-term notes payable             $ 82,500,000      
Issuance of common stock shares par value | (per share)         € 0.10 € 0.10 $ 0.12 $ 0.12 € 0.10  
Term Loan Impairment Loss Recognized             $ 0      
Amended and Restated Loan Agreement [Member]                    
Notes Receivable [Line Items]                    
Loan agreement $ 6,000,000.0                  
Term Loan Receivable [Member]                    
Notes Receivable [Line Items]                    
Loans and lease receivable, Outstanding             5,500,000 $ 2,500,000    
Interest expense       $ 400,000            
Long-Term Debt, Fair Value             5,500,000      
Loans Receivable [Member]                    
Notes Receivable [Line Items]                    
Receivables, Maturity description       On May 14, 2021, the Company amended the loan agreement under which the Maturity Date will be the first business day following the first closing of a subscription for additional units if the proceeds from such subscription amount to at least $3.0 million            
IntelGenx Corp [Member]                    
Notes Receivable [Line Items]                    
Loans receivable, Fixed interest rate         8.00%          
IntelGenx Corp [Member] | Additional Term Loan And March Term Loan [Member]                    
Notes Receivable [Line Items]                    
Payments to acquire notes receivable   $ 500,000                
IntelGenx Corp [Member] | March Term Loan Receivable [Member]                    
Notes Receivable [Line Items]                    
Receivable, Face amount                   $ 2,000,000.0
IntelGenx Corp [Member] | Additional Term Loan Receivable [Member]                    
Notes Receivable [Line Items]                    
Receivable, Face amount                   $ 500,000
IntelGenx Corp [Member] | Additional Term Loan Receivable [Member] | Amended and Restated Loan Agreement [Member]                    
Notes Receivable [Line Items]                    
Receivable, Face amount 6,000.0                  
IntelGenx Corp [Member] | Additional Term Loan Receivable [Member] | Second Tranche [Member] | Amended and Restated Loan Agreement [Member]                    
Notes Receivable [Line Items]                    
Receivable, Face amount 3,000,000.0                  
IntelGenx Corp [Member] | Term Loan Receivable [Member]                    
Notes Receivable [Line Items]                    
Receivable, Face amount $ 8,500,000                  
IntelGenx Corp [Member] | Term Loan Receivable [Member] | Amended and Restated Loan Agreement [Member]                    
Notes Receivable [Line Items]                    
Term loan maturity date Jan. 05, 2024                  
DemeRx Note [Member]                    
Notes Receivable [Line Items]                    
Receivables, Maturity terms     5 years              
Loans and lease receivable, Outstanding             $ 1,100,000 $ 1,100,000    
DemeRx Note [Member] | DemeRx IB, Inc. [Member]                    
Notes Receivable [Line Items]                    
Issuance of common stock shares par value | $ / shares     $ 0.0001              
DemeRx Note [Member] | DemeRx [Member]                    
Notes Receivable [Line Items]                    
Debt Instrument, face amount inclusive other payments     $ 1,000,000.0