XML 132 R12.htm IDEA: XBRL DOCUMENT v3.24.1
Research and development expenses
12 Months Ended
Dec. 31, 2023
Research and development expenses  
Research and development expenses

5.

Research and development expenses

Research and development expenses include the following categories:

For the Year Ended December 31, 

(in thousands)

  

2023

    

2022

    

2021

Pre-clinical and clinical trial expenses

$

20,421

$

28,178

$

14,188

Personnel-related expenses

6,629

6,150

4,955

Research and development activities expenses

2,680

2,241

1,843

Facilities and other research and development expenses

2,356

1,546

814

Share-based compensation expense

1,728

1,975

788

Amsterdam UMC and other license expenses

-

15

14,357

$

33,814

$

40,105

$

36,945

Refer to Note 23 for additional information about Amsterdam UMC license expenses. Government grants, which are a reduction of payroll taxes in the Netherlands, amounted to $2.0 million in 2023, $1.6 million in 2022 and $1.7 million in 2021. These amounts are an offset to wages and salaries that are part of its research and development expenses in the income statement.