Summary of Significant Accounting Policies - Additional Information (Details)	12 Months Ended
	Dec. 31, 2021 USD ($) Segment	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Jun. 30, 2021 shares
Summary Of Significant Accounting Policies [Line Items]
Impairment losses	$ 0	$ 0	$ 0
Percentage of tax benefit realized	50.00%
Success payment liability, payable	$ 6,250,000
Number of operating segment | Segment	1
Operating lease liability	$ 108,758,000
Operating lease right-of-use assets	$ 1,839,000	$ 0
ASC 842
Summary Of Significant Accounting Policies [Line Items]
Change in accounting principle, accounting standards update, adopted	true
Change in accounting principle, accounting standards update, adoption date	Jan. 01, 2021
Operating lease liability	$ 2,600,000
Operating lease right-of-use assets	$ 2,400,000
Change in accounting principle, accounting standards update, immaterial effect	true
Harvard and Board
Summary Of Significant Accounting Policies [Line Items]
Success payment liability, payable	$ 10,000,000,000.0
Issuance of Additional Common Stock | shares				878,098
Success Liability Payment	$ 6,300,000