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Intellectual Property Licenses - License Agreements (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Aug. 31, 2016
USD ($)
item
shares
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Sep. 30, 2016
USD ($)
License Agreements          
Research and development   $ 59,201 $ 51,188    
License Agreement | AskGene          
License Agreements          
Research and development       $ 6,000  
License Agreement | AskGene | IL-15 products          
License Agreements          
Upfront payments payable       6,000  
License Agreement | AskGene | Maximum | IL-15 products          
License Agreements          
Regulatory milestone payments payable       $ 13,000  
License Agreement | City of Hope          
License Agreements          
Research and development   10 10    
Costs incurred related to payment of specified development milestones   0 300    
Number of shares of common stock issued | shares 24,019        
Number of licensed products or services | item 3        
License Agreement | City of Hope | Maximum          
License Agreements          
Development and regulatory milestones payable $ 10,300        
License Agreement | WuXi Biologics          
License Agreements          
Costs incurred related to payment of specified development milestones   $ 0 $ 800    
Development and regulatory milestones payable         $ 25,800