Share-based Compensation Plans (Tables)

3 Months Ended

Mar. 31, 2023

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Option Activity

A summary of option activity for the three-month period ended March 31, 2023 is presented below:

	Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (in years)		Aggregate Intrinsic Value
Outstanding at December 31, 2022		6,148,447		$	1.97
Granted		648,373			2.31
Exercised		(61,844	)		0.01
Forfeited		—			—
Expired		(14,610	)		3.03
Outstanding at March 31, 2023		6,720,366		$	2.02		7.97	$	4,047,686
Vested or expected to vest at March 31, 2023		6,720,366		$	2.02		7.97	$	4,047,686
Exercisable at March 31, 2023		3,594,127		$	1.23		7.22	$	4,027,006

Summary of Non-vested Stock Activity

A summary of non-vested stock activity for the three-month period ended March 31, 2023 is presented below:

	Nonvested Shares			Weighted Average Grant Date Fair Value
Outstanding at December 31, 2022		726,163		$	3.01
Granted		666,810			2.30
Vested		(507,217	)		2.34
Forfeited		—			—
Outstanding at March 31, 2023		885,756		$	2.87

Summary of Share-based Compensation Expense

The impact on the Company’s results of operations from share-based compensation for the three months ended March 31, 2023 and 2022, was as follows (in thousands):

	Three Months Ended March 31,
	2023		2022
Research and development	$	141	$	118
General and administrative		780		668
Total share-based compensation expense	$	921	$	786