The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
51JOB INC SPONSORED ADS 316827104 723 12,343 SH   DFND 1 12,343 0 0
ABBVIE INC COM 00287Y109 7,518 46,376 SH   DFND 1 46,376 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 76,850 1,172,739 SH   DFND 1 1,172,739 0 0
ACUITY BRANDS INC COM 00508Y102 519 2,741 SH   DFND 1 2,741 0 0
ADDUS HOMECARE CORP COM 006739106 32,306 346,297 SH   DFND 1 346,297 0 0
ADICET BIO INC COM 007002108 30,827 1,543,670 SH   DFND 1 1,543,670 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 94,306 206,983 SH   DFND 1 206,983 0 0
ADVANCED ENERGY INDS COM 007973100 254 2,953 SH   DFND 1 2,953 0 0
ADVANCED MICRO DEVICES INC COM 007903107 401,304 3,670,237 SH   DFND 1 3,670,237 0 0
AEVA TECHNOLOGIES INC COM 00835Q103 98 22,601 SH   DFND 1 22,601 0 0
AEYE INC CL A COM 008183105 89 16,327 SH   DFND 1 16,327 0 0
AFFILIATED MANAGERS GROUP IN COM 008252108 22,285 158,104 SH   DFND 1 158,104 0 0
AFLAC INC COM 001055102 27,527 427,500 SH   DFND 1 427,500 0 0
AIR PRODS & CHEMS INC COM 009158106 1,520 6,083 SH   DFND 1 6,083 0 0
AIR TRANS SVCS GROUP INC NOTE 1.125%10/1 00922RAB1 23,343 19,615,000 SH   DFND 1 19,615,000 0 0
AIRBNB INC COM CL A 009066101 130,701 760,951 SH   DFND 1 760,951 0 0
AKOYA BIOSCIENCES INC COM 00974H104 14,457 1,315,470 SH   DFND 1 1,315,470 0 0
ALARM COM HLDGS INC COM 011642105 261 3,920 SH   DFND 1 3,920 0 0
ALBEMARLE CORP COM 012653101 1,765 7,983 SH   DFND 1 7,983 0 0
ALCON AG ORD SHS H01301128 37,048 479,942 SH   DFND 1,2 479,942 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 74,948 688,864 SH   DFND 1 688,864 0 0
ALLEGHANY CORP MD COM 017175100 137,214 162,000 SH   DFND 1 162,000 0 0
ALLEGRO MICROSYSTEMS INC COM 01749D105 569 20,033 SH   DFND 1 20,033 0 0
ALLSCRIPTS HEALTHCARE SOLUTN COM 01988P108 250 11,080 SH   DFND 1 11,080 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 37,529 229,833 SH   DFND 1 229,833 0 0
ALPHABET INC CAP STK CL C 02079K107 564,388 202,073 SH   DFND 1,2 202,073 0 0
ALPHABET INC CAP STK CL A 02079K305 516,956 185,865 SH   DFND 1 185,865 0 0
ALTAIR ENGR INC COM CL A 021369103 536 8,326 SH   DFND 1 8,326 0 0
AMAZON COM INC COM 023135106 307,315 94,270 SH   DFND 1 94,270 0 0
AMBARELLA INC SHS G037AX101 46,468 442,887 SH   DFND 1 442,887 0 0
AMEDISYS INC COM 023436108 14,193 82,380 SH   DFND 1 82,380 0 0
AMERESCO INC CL A 02361E108 321 4,037 SH   DFND 1 4,037 0 0
AMETEK INC COM 031100100 19,478 146,250 SH   DFND 1 146,250 0 0
AMGEN INC COM 031162100 6,944 28,717 SH   DFND 1 28,717 0 0
ANALOG DEVICES INC COM 032654105 29,397 177,972 SH   DFND 1 177,972 0 0
ANGIODYNAMICS INC COM 03475V101 40,546 1,882,375 SH   DFND 1 1,882,375 0 0
ANSYS INC COM 03662Q105 4,756 14,972 SH   DFND 1 14,972 0 0
ANTHEM INC COM 036752103 32,451 66,062 SH   DFND 1 66,062 0 0
AON PLC SHS CL A G0403H108 109,900 337,500 SH   DFND 1 337,500 0 0
APPLE INC COM 037833100 855,404 4,898,940 SH   DFND 1 4,898,940 0 0
APPLE INC COM 037833100 490,654 2,810,000 SH Call DFND 1 2,810,000 0 0
APPLIED MATLS INC COM 038222105 162,707 1,234,498 SH   DFND 1 1,234,498 0 0
APTARGROUP INC COM 038336103 55,366 471,204 SH   DFND 1 471,204 0 0
APTIV PLC SHS G6095L109 886 7,403 SH   DFND 1 7,403 0 0
ARCH CAP GROUP LTD ORD G0450A105 260,319 5,376,273 SH   DFND 1 5,376,273 0 0
ARCHER AVIATION INC COM CL A 03945R102 121 25,064 SH   DFND 1 25,064 0 0
ARCO PLATFORM LTD COM CL A G04553106 11,525 546,227 SH   DFND 1 546,227 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 34,360 1,784,005 SH   DFND 1 1,784,005 0 0
ARES CAPITAL CORP COM 04010L103 5,238 250,000 SH Put DFND 1 250,000 0 0
ARES CAPITAL CORP COM 04010L103 5,504 262,753 SH   DFND 1 262,753 0 0
ARISTA NETWORKS INC COM 040413106 178,290 1,282,844 SH   DFND 1 1,282,844 0 0
ARRAY TECHNOLOGIES INC COM SHS 04271T100 119 10,573 SH   DFND 1 10,573 0 0
ARRIVAL GROUP SHS L0423Q108 249 66,714 SH   DFND 1 66,714 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 790 17,182 SH   DFND 1 17,182 0 0
ATLASSIAN CORP PLC CL A G06242104 19,919 67,792 SH   DFND 1 67,792 0 0
ATRICURE INC COM 04963C209 34,730 528,858 SH   DFND 1 528,858 0 0
AURORA INNOVATION INC CLASS A COM 051774107 524 93,789 SH   DFND 1 93,789 0 0
AUTODESK INC COM 052769106 597 2,785 SH   DFND 1 2,785 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 21,850 3,199,152 SH   DFND 1 3,199,152 0 0
AVANTOR INC COM 05352A100 64,343 1,902,503 SH   DFND 1 1,902,503 0 0
AXON ENTERPRISE INC COM 05464C101 32,319 234,656 SH   DFND 1 234,656 0 0
AXONICS INC COM 05465P101 44,467 710,336 SH   DFND 1 710,336 0 0
BAKER HUGHES COMPANY CL A 05722G100 8,458 232,303 SH   DFND 1 232,303 0 0
BALLARD PWR SYS INC NEW COM 058586108 711 54,746 SH   DFND 1 54,746 0 0
BANK NEW YORK MELLON CORP COM 064058100 6,100 122,900 SH   DFND 1 122,900 0 0
BANK OF NT BUTTERFIELD&SON L SHS NEW G0772R208 9,122 254,235 SH   DFND 1 254,235 0 0
BAXTER INTL INC COM 071813109 18,376 236,993 SH   DFND 1 236,993 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 22,360 3,250,000 SH   DFND 1 3,250,000 0 0
BERKLEY W R CORP COM 084423102 118,738 1,783,125 SH   DFND 1 1,783,125 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 101,927 288,820 SH   DFND 1 288,820 0 0
BIO RAD LABS INC CL A 090572207 62,967 111,796 SH   DFND 1 111,796 0 0
BIOGEN INC COM 09062X103 26,325 125,000 SH   DFND 1 125,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 146,625 1,236,609 SH   DFND 1 1,236,609 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 38,550 500,000 SH   DFND 1 500,000 0 0
BIRD GLOBAL INC COM CL A 09077J107 71 28,973 SH   DFND 1 28,973 0 0
BK OF AMERICA CORP COM 060505104 28,050 680,490 SH   DFND 1 680,490 0 0
BLACKLINE INC NOTE 3/1 09239BAD1 25,500 30,000,000 SH   DFND 1 30,000,000 0 0
BLACKSTONE INC COM 09260D107 11,560 91,063 SH   DFND 1 91,063 0 0
BLINK CHARGING CO COM 09354A100 205 7,762 SH   DFND 1 7,762 0 0
BLOCK INC NOTE 5/0 852234AJ2 6,505 7,000,000 SH   DFND 1 7,000,000 0 0
BLOCK INC CL A 852234103 25,681 189,385 SH   DFND 1 189,385 0 0
BLOOM ENERGY CORP COM CL A 093712107 332 13,739 SH   DFND 1 13,739 0 0
BOOKING HOLDINGS INC COM 09857L108 21,143 9,003 SH   DFND 1 9,003 0 0
BORGWARNER INC COM 099724106 915 23,526 SH   DFND 1 23,526 0 0
BOSTON SCIENTIFIC CORP COM 101137107 95,501 2,156,268 SH   DFND 1 2,156,268 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 31,943 437,401 SH   DFND 1 437,401 0 0
BROADCOM INC COM 11135F101 821 1,304 SH   DFND 1 1,304 0 0
CANADIAN NAT RES LTD COM 136385101 32,955 474,996 SH   DFND 1 474,996 0 0
CANNAE HLDGS INC COM 13765N107 10,171 425,215 SH   DFND 1 425,215 0 0
CANOO INC COM CL A 13803R102 139 25,218 SH   DFND 1 25,218 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 662 14,435 SH   DFND 1 14,435 0 0
CASTLE BIOSCIENCES INC COM 14843C105 2,018 44,985 SH   DFND 1 44,985 0 0
CATALENT INC COM 148806102 5,382 48,527 SH   DFND 1 48,527 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 42,575 1,250,000 SH   DFND 1 1,250,000 0 0
CENOVUS ENERGY INC COM 15135U109 23,240 1,250,032 SH   DFND 1 1,250,032 0 0
CENTENE CORP DEL COM 15135B101 21,226 252,115 SH   DFND 1 252,115 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 26,258 750,000 SH   DFND 1 750,000 0 0
CERUS CORP COM 157085101 11,147 2,030,337 SH   DFND 1 2,030,337 0 0
CHARGEPOINT HOLDINGS INC COM CL A 15961R105 1,239 62,322 SH   DFND 1 62,322 0 0
CHART INDS INC COM 16115Q308 1,149 6,692 SH   DFND 1 6,692 0 0
CHEMED CORP NEW COM 16359R103 6,858 13,539 SH   DFND 1 13,539 0 0
CHUBB LIMITED COM H1467J104 224,504 1,049,576 SH   DFND 1 1,049,576 0 0
CITIZENS FINL GROUP INC COM 174610105 15,266 336,764 SH   DFND 1 336,764 0 0
CITRIX SYS INC COM 177376100 835 8,277 SH   DFND 1 8,277 0 0
CLOUDFLARE INC CL A COM 18915M107 70,265 587,006 SH   DFND 1 587,006 0 0
COGNEX CORP COM 192422103 4,761 61,706 SH   DFND 1 61,706 0 0
CONSTELLIUM SE CL A SHS F21107101 266 14,784 SH   DFND 1 14,784 0 0
COOPER COS INC COM NEW 216648402 72,036 172,504 SH   DFND 1 172,504 0 0
COUPA SOFTWARE INC NOTE 0.125% 6/1 22266LAC0 2,928 3,000,000 SH   DFND 1 3,000,000 0 0
COUPA SOFTWARE INC NOTE 0.375% 6/1 22266LAF3 20,678 24,500,000 SH   DFND 1 24,500,000 0 0
COUPA SOFTWARE INC COM 22266L106 11,071 108,933 SH   DFND 1 108,933 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 159,704 703,293 SH   DFND 1 703,293 0 0
CS DISCO INC COM 126327105 5,932 174,619 SH   DFND 1 174,619 0 0
CUMMINS INC COM 231021106 999 4,872 SH   DFND 1 4,872 0 0
CURIS INC COM NEW 231269200 1,701 714,700 SH   DFND 1 714,700 0 0
CVS HEALTH CORP COM 126650100 69,374 685,444 SH   DFND 1 685,444 0 0
CYBERARK SOFTWARE LTD NOTE 11/1 23248VAB1 3,733 3,000,000 SH   DFND 1 3,000,000 0 0
CYBERARK SOFTWARE LTD SHS M2682V108 119,812 709,998 SH   DFND 1 709,998 0 0
CYTOKINETICS INC COM NEW 23282W605 117,104 3,181,300 SH   DFND 1 3,181,300 0 0
DANA INC COM 235825205 269 15,317 SH   DFND 1 15,317 0 0
DEERE & CO COM 244199105 3,140 7,559 SH   DFND 1 7,559 0 0
DEXCOM INC NOTE 0.250%11/1 252131AK3 1,720 1,500,000 SH   DFND 1 1,500,000 0 0
DEXCOM INC COM 252131107 24,452 47,795 SH   DFND 1 47,795 0 0
DIDI GLOBAL INC SPONSORED ADS 23292E108 530 212,061 SH   DFND 1 212,061 0 0
DIODES INC COM 254543101 307 3,525 SH   DFND 1 3,525 0 0
DISH NETWORK CORPORATION NOTE 12/1 25470MAF6 23,890 24,500,000 SH   DFND 1 24,500,000 0 0
DOCUSIGN INC COM 256163106 16,359 152,716 SH   DFND 1 152,716 0 0
DOLBY LABORATORIES INC COM CL A 25659T107 14,712 188,084 SH   DFND 1 188,084 0 0
DOLLAR GEN CORP NEW COM 256677105 3,365 15,115 SH   DFND 2 15,115 0 0
DOORDASH INC CL A 25809K105 8,523 72,726 SH   DFND 1 72,726 0 0
DROPBOX INC NOTE 3/0 26210CAC8 8,442 9,000,000 SH   DFND 1 9,000,000 0 0
DUN & BRADSTREET HLDGS INC COM 26484T106 4,046 230,913 SH   DFND 2 230,913 0 0
EAST WEST BANCORP INC COM 27579R104 16,692 211,238 SH   DFND 1 211,238 0 0
EATON CORP PLC SHS G29183103 691 4,555 SH   DFND 1 4,555 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 11,381 96,679 SH   DFND 1 96,679 0 0
ELASTIC N V ORD SHS N14506104 101,331 1,139,191 SH   DFND 1 1,139,191 0 0
ELECTRAMECCANICA VEHS CORP COM NEW 284849205 26 12,139 SH   DFND 1 12,139 0 0
ELECTRIC LAST MILE SOLUTNS I CLASS A COM 28489L104 20 13,759 SH   DFND 1 13,759 0 0
EMBARK TECHNOLOGY INC COM 29079J103 225 38,279 SH   DFND 1 38,279 0 0
EMERSON ELEC CO COM 291011104 17,088 174,278 SH   DFND 1 174,278 0 0
ENCOMPASS HEALTH CORP COM 29261A100 62,635 880,823 SH   DFND 1 880,823 0 0
ENERSYS COM 29275Y102 4,503 60,388 SH   DFND 1 60,388 0 0
ENOVIX CORPORATION COM 293594107 381 26,710 SH   DFND 1 26,710 0 0
ENPHASE ENERGY INC COM 29355A107 6,927 34,330 SH   DFND 1 34,330 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 10,402 219,866 SH   DFND 1 219,866 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 78,644 1,614,543 SH   DFND 1 1,614,543 0 0
ESQUIRE FINL HLDGS INC COM 29667J101 710 21,123 SH   DFND 1 21,123 0 0
ESS TECH INC COMMON STOCK 26916J106 66 11,816 SH   DFND 1 11,816 0 0
ESSENT GROUP LTD COM G3198U102 98,389 2,387,500 SH   DFND 1 2,387,500 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 397 5,891 SH   DFND 1 5,891 0 0
ETSY INC COM 29786A106 4,020 32,350 SH   DFND 1 32,350 0 0
EVEREST RE GROUP LTD COM G3223R108 76,324 253,250 SH   DFND 1 253,250 0 0
EVGO INC CL A COM 30052F100 626 48,649 SH   DFND 1 48,649 0 0
EVOLENT HEALTH INC CL A 30050B101 1,292 40,008 SH   DFND 1 40,008 0 0
EXACT SCIENCES CORP NOTE 0.375% 3/0 30063PAC9 2,210 2,500,000 SH   DFND 1 2,500,000 0 0
EXELIXIS INC COM 30161Q104 53,511 2,360,447 SH   DFND 1 2,360,447 0 0
FARADAY FUTRE INTLGT ELCTR I COM 307359109 298 59,651 SH   DFND 1 59,651 0 0
FERGUSON PLC NEW SHS G3421J106 4,689,446 278,548 SH   DFND 1 278,548 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 17,638 175,643 SH   DFND 2 175,643 0 0
FIRST AMERN FINL CORP COM 31847R102 38,082 587,500 SH   DFND 1 587,500 0 0
FIRST SOLAR INC COM 336433107 697 8,326 SH   DFND 1 8,326 0 0
FISERV INC COM 337738108 11,302 111,460 SH   DFND 1 111,460 0 0
FISKER INC CL A COM STK 33813J106 704 54,569 SH   DFND 1 54,569 0 0
FIVE9 INC COM 338307101 130,756 1,184,388 SH   DFND 1 1,184,388 0 0
FLUENCE ENERGY INC COM CL A 34379V103 176 13,413 SH   DFND 1 13,413 0 0
FORD MTR CO DEL NOTE 3/1 345370CZ1 16,025 13,500,000 SH   DFND 1 13,500,000 0 0
FREYR BATTERY SHS L4135L100 263 21,412 SH   DFND 1 21,412 0 0
FUELCELL ENERGY INC COM 35952H601 165 28,710 SH   DFND 1 28,710 0 0
FULCRUM THERAPEUTICS INC COM 359616109 11,825 500,000 SH   DFND 1 500,000 0 0
GARMIN LTD SHS H2906T109 925 7,802 SH   DFND 1 7,802 0 0
GENERAC HLDGS INC COM 368736104 661 2,224 SH   DFND 1 2,224 0 0
GENERAL DYNAMICS CORP COM 369550108 2,554 10,591 SH   DFND 2 10,591 0 0
GENTEX CORP COM 371901109 731 25,063 SH   DFND 1 25,063 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 37,959 1,095,810 SH   DFND 1 1,095,810 0 0
GLOBUS MED INC CL A 379577208 53,706 727,918 SH   DFND 1 727,918 0 0
GOLUB CAP BDC INC COM 38173M102 4,478 294,430 SH   DFND 1 294,430 0 0
GUARDANT HEALTH INC COM 40131M109 4,451 67,197 SH   DFND 1 67,197 0 0
GUARDANT HEALTH INC NOTE 11/1 40131MAB5 24,415 30,250,000 SH   DFND 1 30,250,000 0 0
HARMONY BIOSCIENCES HLDGS IN COM 413197104 26,758 550,000 SH   DFND 1 550,000 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 876 14,279 SH   DFND 1 14,279 0 0
HEALTH CATALYST INC COM 42225T107 386 14,755 SH   DFND 1 14,755 0 0
HEALTHEQUITY INC COM 42226A107 448 6,645 SH   DFND 1 6,645 0 0
HELIOGEN INC COMMON STOCK 42329E105 199 37,835 SH   DFND 1 37,835 0 0
HOLOGIC INC COM 436440101 15,052 195,937 SH   DFND 1 195,937 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 157,077 1,492,989 SH   DFND 1 1,492,989 0 0
HUAZHU GROUP LTD SPONSORED ADS 44332N106 347 10,515 SH   DFND 1 10,515 0 0
HUBBELL INC COM 443510607 695 3,782 SH   DFND 1 3,782 0 0
HUBSPOT INC NOTE 0.375% 6/0 443573AD2 3,572 2,000,000 SH   DFND 1 2,000,000 0 0
HUBSPOT INC COM 443573100 145,440 306,228 SH   DFND 1 306,228 0 0
HYLIION HOLDINGS CORP COMMON STOCK 449109107 141 31,874 SH   DFND 1 31,874 0 0
HYZON MOTORS INC COM CL A 44951Y102 167 26,153 SH   DFND 1 26,153 0 0
IAC INTERACTIVECORP NEW COM NEW 44891N208 14,916 148,741 SH   DFND 1 148,741 0 0
ICON PLC SHS G4705A100 17,227 70,828 SH   DFND 1 70,828 0 0
IDEANOMICS INC COM 45166V106 59 52,558 SH   DFND 1 52,558 0 0
II-VI INC COM 902104108 602 8,311 SH   DFND 1 8,311 0 0
IMPINJ INC COM 453204109 5,524 86,940 SH   DFND 1 86,940 0 0
INCYTE CORP COM 45337C102 80,404 1,012,386 SH   DFND 1 1,012,386 0 0
INDIE SEMICONDUCTOR INC CLASS A COM 45569U101 107 13,737 SH   DFND 1 13,737 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 5,700 5,000,000 SH   DFND 1 5,000,000 0 0
INNOVIZ TECHNOLOGIES LTD SHS M5R635108 51 14,120 SH   DFND 1 14,120 0 0
INSMED INC COM PAR $.01 457669307 14,848 631,849 SH   DFND 1 631,849 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 18,713 257,510 SH   DFND 1 257,510 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 29,952 226,703 SH   DFND 1 226,703 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 31,907 521,443 SH   DFND 1 521,443 0 0
INTUIT COM 461202103 7,960 16,554 SH   DFND 1 16,554 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 17,079 56,612 SH   DFND 1 56,612 0 0
IPG PHOTONICS CORP COM 44980X109 458 4,174 SH   DFND 1 4,174 0 0
IQIYI INC NOTE 2.000% 4/0 46267XAD0 80 100,000 SH   DFND 1 100,000 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 1,526 9,691 SH   DFND 1 9,691 0 0
ITRON INC COM 465741106 3,585 68,045 SH   DFND 1 68,045 0 0
IVERIC BIO INC COM 46583P102 31,449 1,868,628 SH   DFND 1 1,868,628 0 0
JAMES RIV GROUP LTD COM G5005R107 22,266 900,000 SH   DFND 1 900,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 15,567 100,000 SH   DFND 1 100,000 0 0
JD.COM INC SPON ADR CL A 47215P106 618 10,680 SH   DFND 1 10,680 0 0
JOBY AVIATION INC COMMON STOCK G65163100 422 63,776 SH   DFND 1 63,776 0 0
JOHNSON & JOHNSON COM 478160104 53,342 300,975 SH   DFND 1 300,975 0 0
JOHNSON CTLS INTL PLC SHS G51502105 4,477 68,281 SH   DFND 1 68,281 0 0
JPMORGAN CHASE & CO COM 46625H100 35,237 258,485 SH   DFND 1 258,485 0 0
KE HLDGS INC SPONSORED ADS 482497104 298 24,087 SH   DFND 1 24,087 0 0
KLA CORP COM NEW 482480100 166,221 454,081 SH   DFND 1 454,081 0 0
KORNIT DIGITAL LTD SHS M6372Q113 60,645 733,398 SH   DFND 1 733,398 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 7,376 27,975 SH   DFND 1,2 27,975 0 0
LANTHEUS HLDGS INC COM 516544103 1,397 25,256 SH   DFND 1 25,256 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 138,836 2,277,869 SH   DFND 1 2,277,869 0 0
LEAR CORP COM NEW 521865204 828 5,804 SH   DFND 1 5,804 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 13,623 374,870 SH   DFND 1 374,870 0 0
LI AUTO INC SPONSORED ADS 50202M102 1,479 57,292 SH   DFND 1 57,292 0 0
LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 12,915 184,917 SH   DFND 1 184,917 0 0
LI-CYCLE HOLDINGS CORP COMMON SHARES 50202P105 254 30,008 SH   DFND 1 30,008 0 0
LILIUM N V CLASS A ORD SHS N52586109 119 30,004 SH   DFND 1 30,004 0 0
LILLY ELI & CO COM 532457108 12,958 45,248 SH   DFND 1 45,248 0 0
LINDE PLC SHS G5494J103 27,723 75,606 SH   DFND 1 75,606 0 0
LITHIUM AMERS CORP NEW COM NEW 53680Q207 949 22,108 SH   DFND 1 22,108 0 0
LITTELFUSE INC COM 537008104 16,574 66,454 SH   DFND 1 66,454 0 0
LIVANOVA PLC SHS G5509L101 56,250 687,395 SH   DFND 1 687,395 0 0
LIVENT CORP COM 53814L108 1,218 46,714 SH   DFND 1 46,714 0 0
LIVERAMP HLDGS INC COM 53815P108 3,954 105,750 SH   DFND 1 105,750 0 0
LOGITECH INTL S A SHS H50430232 7,148 98,622 SH   DFND 1 98,622 0 0
LORDSTOWN MOTORS CORP COM CL A 54405Q100 69 20,300 SH   DFND 1 20,300 0 0
LPL FINL HLDGS INC COM 50212V100 23,722 129,858 SH   DFND 1 129,858 0 0
LUCID GROUP INC COM 549498103 1,228 48,332 SH   DFND 1 48,332 0 0
LUMENTUM HLDGS INC COM 55024U109 3,793 38,861 SH   DFND 1 38,861 0 0
LUMINAR TECHNOLOGIES INC COM CL A 550424105 597 38,182 SH   DFND 1 38,182 0 0
LYFT INC CL A COM 55087P104 949 24,714 SH   DFND 1 24,714 0 0
MAGNA INTL INC COM 559222401 940 13,130 SH   DFND 1 13,130 0 0
MARKEL CORP COM 570535104 145,680 98,750 SH   DFND 1 98,750 0 0
MARSH & MCLENNAN COS INC COM 571748102 196,282 1,151,757 SH   DFND 1 1,151,757 0 0
MARVELL TECHNOLOGY INC COM 573874104 212,879 2,968,605 SH   DFND 1 2,968,605 0 0
MASTEC INC COM 576323109 507 5,818 SH   DFND 1 5,818 0 0
MASTERCARD INCORPORATED CL A 57636Q104 102,894 287,913 SH   DFND 1 287,913 0 0
MATCH GROUP INC NEW COM 57667L107 91,359 840,157 SH   DFND 1 840,157 0 0
MEDTRONIC PLC SHS G5960L103 25,473 229,588 SH   DFND 1 229,588 0 0
MERCADOLIBRE INC COM 58733R102 40,508 34,055 SH   DFND 1 34,055 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 562 21,635 SH   DFND 1 21,635 0 0
MERIT MED SYS INC COM 589889104 37,467 563,251 SH   DFND 1 563,251 0 0
META PLATFORMS INC CL A 30303M102 148,072 665,913 SH   DFND 1 665,913 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 678 9,025 SH   DFND 1 9,025 0 0
MICRON TECHNOLOGY INC COM 595112103 168,844 2,167,728 SH   DFND 1 2,167,728 0 0
MICROSOFT CORP COM 594918104 1,115,837 3,619,204 SH   DFND 1,2 3,619,204 0 0
MICROVAST HOLDINGS INC COM 59516C106 370 55,267 SH   DFND 1 55,267 0 0
MIDDLEBY CORP NOTE 1.000% 9/0 596278AB7 4,146 3,000,000 SH   DFND 1 3,000,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 2,416 29,390 SH   DFND 1 29,390 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 21,441 973,709 SH   DFND 1 973,709 0 0
MKS INSTRS INC COM 55306N104 24,938 166,250 SH   DFND 1 166,250 0 0
MODIVCARE INC COM 60783X104 8,553 74,125 SH   DFND 1 74,125 0 0
MOHAWK INDS INC COM 608190104 4,358 35,088 SH   DFND 1 35,088 0 0
MOLINA HEALTHCARE INC COM 60855R100 68,627 205,723 SH   DFND 1 205,723 0 0
MONGODB INC CL A 60937P106 78,043 175,936 SH   DFND 1 175,936 0 0
MONOLITHIC PWR SYS INC COM 609839105 91,502 188,399 SH   DFND 1 188,399 0 0
MORGAN STANLEY COM NEW 617446448 8,789 100,558 SH   DFND 1 100,558 0 0
MORPHIC HLDG INC COM 61775R105 13,049 325,000 SH   DFND 1 325,000 0 0
MP MATERIALS CORP COM CL A 553368101 8,011 139,712 SH   DFND 1 139,712 0 0
MSCI INC COM 55354G100 4,414 8,778 SH   DFND 1 8,778 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 56,216 1,617,733 SH   DFND 1 1,617,733 0 0
NATERA INC COM 632307104 5,282 129,832 SH   DFND 1 129,832 0 0
NATIONAL INSTRS CORP COM 636518102 422 10,397 SH   DFND 1 10,397 0 0
NAVITAS SEMICONDUCTOR CORP COM 63942X106 1,544 150,218 SH   DFND 1 150,218 0 0
NETEASE INC SPONSORED ADS 64110W102 532 5,934 SH   DFND 1 5,934 0 0
NETFLIX INC COM 64110L106 84,143 224,627 SH   DFND 1 224,627 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 71,183 759,287 SH   DFND 1 759,287 0 0
NEVRO CORP COM 64157F103 3,374 46,647 SH   DFND 1 46,647 0 0
NEXTNAV INC COMMON STOCK 65345N106 76 10,082 SH   DFND 1 10,082 0 0
NIKOLA CORP COM 654110105 460 42,970 SH   DFND 1 42,970 0 0
NIO INC SPON ADS 62914V106 5,221 248,049 SH   DFND 1 248,049 0 0
NIU TECHNOLOGIES ADS 65481N100 1,758 182,029 SH   DFND 1 182,029 0 0
NORFOLK SOUTHN CORP COM 655844108 10,888 38,174 SH   DFND 1 38,174 0 0
NORTONLIFELOCK INC NOTE 2.000% 8/1 668771AB4 4,629 3,500,000 SH   DFND 1 3,500,000 0 0
NVIDIA CORPORATION COM 67066G104 462,088 1,693,500 SH   DFND 1 1,693,500 0 0
NXP SEMICONDUCTORS N V COM N6596X109 1,686 9,112 SH   DFND 1 9,112 0 0
OAK STR HEALTH INC COM 67181A107 2,298 85,500 SH   DFND 1 85,500 0 0
OCULAR THERAPEUTIX INC COM 67576A100 187 37,790 SH   DFND 1 37,790 0 0
OKTA INC CL A 679295105 79,929 529,473 SH   DFND 1 529,473 0 0
OMNICELL COM COM 68213N109 1,037 8,007 SH   DFND 1 8,007 0 0
ON SEMICONDUCTOR CORP COM 682189105 103,037 1,645,688 SH   DFND 1 1,645,688 0 0
OPTION CARE HEALTH INC COM NEW 68404L201 49,895 1,747,020 SH   DFND 1 1,747,020 0 0
ORACLE CORP COM 68389X105 3,209 38,791 SH   DFND 2 38,791 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 2,967 4,331 SH   DFND 1,2 4,331 0 0
ORGANON & CO COMMON STOCK 68622V106 736 21,058 SH   DFND 1 21,058 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 402 21,567 SH   DFND 1 21,567 0 0
OTONOMO TECHNOLOGIES LTD ORDINARY SHARES M7571L103 28 13,962 SH   DFND 1 13,962 0 0
OUSTER INC COM 68989M103 82 18,122 SH   DFND 1 18,122 0 0
OWENS & MINOR INC NEW COM 690732102 655 14,888 SH   DFND 1 14,888 0 0
PACIRA BIOSCIENCES INC COM 695127100 255 3,345 SH   DFND 1 3,345 0 0
PACWEST BANCORP DEL COM 695263103 11,268 261,257 SH   DFND 1 261,257 0 0
PALO ALTO NETWORKS INC COM 697435105 92,641 148,818 SH   DFND 1 148,818 0 0
PAYCOM SOFTWARE INC COM 70432V102 11,978 34,581 SH   DFND 1 34,581 0 0
PAYPAL HLDGS INC COM 70450Y103 24,876 215,101 SH   DFND 1 215,101 0 0
PENUMBRA INC COM 70975L107 3,732 16,801 SH   DFND 1 16,801 0 0
PHOENIX NEW MEDIA LTD SPONSORED ADS 71910C103 66 116,984 SH   DFND 1 116,984 0 0
PIONEER NAT RES CO NOTE 0.250% 5/1 723787AP2 2,380 1,000,000 SH   DFND 1 1,000,000 0 0
PLUG POWER INC COM NEW 72919P202 6,785 237,146 SH   DFND 1 237,146 0 0
PNC FINL SVCS GROUP INC COM 693475105 16,316 88,457 SH   DFND 1 88,457 0 0
POWER INTEGRATIONS INC COM 739276103 60,857 656,640 SH   DFND 1 656,640 0 0
PROASSURANCE CORP COM 74267C106 32,256 1,200,000 SH   DFND 1 1,200,000 0 0
PROGRESSIVE CORP COM 743315103 69,448 609,250 SH   DFND 1 609,250 0 0
PROGYNY INC COM 74340E103 456 8,873 SH   DFND 1 8,873 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 7,185 303,429 SH   DFND 1 303,429 0 0
PROTERRA INC COM 74374T109 173 23,055 SH   DFND 1 23,055 0 0
PTC INC COM 69370C100 696 6,463 SH   DFND 1 6,463 0 0
PURE STORAGE INC CL A 74624M102 138,404 3,919,672 SH   DFND 1 3,919,672 0 0
QIAGEN NV SHS NEW N72482123 2,618 46,522 SH   DFND 1 46,522 0 0
QORVO INC COM 74736K101 621 5,006 SH   DFND 1 5,006 0 0
QUALCOMM INC COM 747525103 113,453 742,397 SH   DFND 1 742,397 0 0
QUALTRICS INTL INC COM CL A 747601201 14,230 498,439 SH   DFND 1 498,439 0 0
QUANTA SVCS INC COM 74762E102 899 6,833 SH   DFND 1 6,833 0 0
QUANTUMSCAPE CORP COM CL A 74767V109 1,554 77,716 SH   DFND 1 77,716 0 0
QUOTIENT LTD SHS G73268107 11,102 9,251,653 SH   DFND 1 9,251,653 0 0
R1 RCM INC COM 749397105 14,034 524,421 SH   DFND 1 524,421 0 0
REE AUTOMOTIVE LTD CLASS A ORD SHS M8287R103 63 33,092 SH   DFND 1 33,092 0 0
REGAL REXNORD CORPORATION COM 758750103 1,462 9,829 SH   DFND 1 9,829 0 0
REGENERON PHARMACEUTICALS COM 75886F107 101,271 145,000 SH   DFND 1 145,000 0 0
REGIONS FINANCIAL CORP NEW COM 7591EP100 7,660 344,122 SH   DFND 1 344,122 0 0
REINSURANCE GRP OF AMERICA I COM NEW 759351604 67,318 615,000 SH   DFND 1 615,000 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 133,034 839,281 SH   DFND 1,2 839,281 0 0
REPLIGEN CORP NOTE 0.375% 7/1 759916AB5 5,174 3,000,000 SH   DFND 1 3,000,000 0 0
RESIDEO TECHNOLOGIES INC COM 76118Y104 1,401 58,805 SH   DFND 1 58,805 0 0
REVANCE THERAPEUTICS INC COM 761330109 47,902 2,456,497 SH   DFND 1 2,456,497 0 0
RINGCENTRAL INC NOTE 3/0 76680RAF4 20,092 22,975,000 SH   DFND 1 22,975,000 0 0
RIVIAN AUTOMOTIVE INC COM CL A 76954A103 891 17,735 SH   DFND 1 17,735 0 0
RLI CORP COM 749607107 30,423 275,000 SH   DFND 1 275,000 0 0
ROBLOX CORP CL A 771049103 60,817 1,315,246 SH   DFND 1 1,315,246 0 0
ROCKWELL AUTOMATION INC COM 773903109 16,073 57,396 SH   DFND 1 57,396 0 0
ROMEO POWER INC COM 776153108 37 24,669 SH   DFND 1 24,669 0 0
ROYAL CARIBBEAN GROUP NOTE 2.875%11/1 780153BF8 4,856 4,000,000 SH   DFND 1 4,000,000 0 0
RYAN SPECIALTY GROUP HLDGS I CL A 78351F107 24,205 624,000 SH   DFND 1 624,000 0 0
S&P GLOBAL INC COM 78409V104 26,156 63,768 SH   DFND 1 63,768 0 0
SABRE CORP COM 78573M104 5,772 504,988 SH   DFND 1 504,988 0 0
SALESFORCE COM INC COM 79466L302 17,232 81,159 SH   DFND 1 81,159 0 0
SAMSARA INC COM CL A 79589L106 602 37,569 SH   DFND 1 37,569 0 0
SEA LTD SPONSORD ADS 81141R100 34,169 285,237 SH   DFND 1 285,237 0 0
SEAGATE TECHNOLOGY HLDNGS PL ORD SHS G7997R103 98,175 1,092,045 SH   DFND 1 1,092,045 0 0
SEAGEN INC COM 81181C104 85,097 590,748 SH   DFND 1 590,748 0 0
SEMTECH CORP COM 816850101 350 5,046 SH   DFND 1 5,046 0 0
SENSATA TECHNOLOGIES HLDG PL SHS G8060N102 14,460 284,366 SH   DFND 1,2 284,366 0 0
SERVICE CORP INTL COM 817565104 23,065 350,419 SH   DFND 1 350,419 0 0
SERVICENOW INC COM 81762P102 239,171 429,477 SH   DFND 1 429,477 0 0
SHIFT4 PMTS INC NOTE 12/1 82452JAB5 13,413 12,750,000 SH   DFND 1 12,750,000 0 0
SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 223 13,064 SH   DFND 1 13,064 0 0
SHOCKWAVE MED INC COM 82489T104 1,093 5,273 SH   DFND 1 5,273 0 0
SHOPIFY INC CL A 82509L107 86,697 128,257 SH   DFND 1 128,257 0 0
SIGNATURE BK NEW YORK N Y COM 82669G104 35,088 119,556 SH   DFND 1 119,556 0 0
SILICON LABORATORIES INC NOTE 0.625% 6/1 826919AD4 10,943 7,941,000 SH   DFND 1 7,941,000 0 0
SILICON LABORATORIES INC COM 826919102 473 3,147 SH   DFND 1 3,147 0 0
SITIME CORP COM 82982T106 79,076 319,088 SH   DFND 1 319,088 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 675 5,067 SH   DFND 1 5,067 0 0
SLR INVESTMENT CORP COM 83413U100 5,142 283,615 SH   DFND 1 283,615 0 0
SLR SENIOR INVESTMENT CORP COM 83416M105 314 22,149 SH   DFND 1 22,149 0 0
SMARTSHEET INC COM CL A 83200N103 69,486 1,268,463 SH   DFND 1 1,268,463 0 0
SMITH A O CORP COM 831865209 585 9,154 SH   DFND 1 9,154 0 0
SNAP INC CL A 83304A106 256,062 7,114,814 SH   DFND 1 7,114,814 0 0
SNOWFLAKE INC CL A 833445109 56,466 246,435 SH   DFND 1 246,435 0 0
SOCIEDAD QUIMICA Y MINERA DE SPON ADR SER B 833635105 3,122 36,467 SH   DFND 1 36,467 0 0
SOLAREDGE TECHNOLOGIES INC COM 83417M104 67,566 209,590 SH   DFND 1 209,590 0 0
SOLID POWER INC CLASS A COM 83422N105 267 30,814 SH   DFND 1 30,814 0 0
SPIRIT AIRLS INC NOTE 1.000% 5/1 848577AB8 3,608 4,000,000 SH   DFND 1 4,000,000 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 1,470 9,737 SH   DFND 2 9,737 0 0
SS&C TECHNOLOGIES HLDGS INC COM 78467J100 29,840 397,760 SH   DFND 1 397,760 0 0
SSR MNG INC NOTE 2.500% 4/0 784730AB9 14,004 10,039,000 SH   DFND 1 10,039,000 0 0
STELLANTIS N.V SHS N82405106 16,425 878,748 SH   DFND 2 878,748 0 0
STEM INC COM 85859N102 125 11,313 SH   DFND 1 11,313 0 0
STEREOTAXIS INC COM NEW 85916J409 286 76,687 SH   DFND 1 76,687 0 0
STERIS PLC SHS USD G8473T100 96,031 397,200 SH   DFND 1 397,200 0 0
STRIDE INC NOTE 1.125% 9/0 86333MAA6 1,496 1,500,000 SH   DFND 1 1,500,000 0 0
STRYKER CORPORATION COM 863667101 12,223 45,719 SH   DFND 1 45,719 0 0
SUMMIT THERAPEUTICS INC COM 86627T108 15,368 6,272,509 SH   DFND 1 6,272,509 0 0
SUNNOVA ENERGY INTL INC. COM 86745K104 203 8,791 SH   DFND 1 8,791 0 0
SUNPOWER CORP COM 867652406 291 13,545 SH   DFND 1 13,545 0 0
SUNRUN INC COM 86771W105 492 16,208 SH   DFND 1 16,208 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 28,375 877,945 SH   DFND 1 877,945 0 0
SURGERY PARTNERS INC COM 86881A100 27,288 495,695 SH   DFND 1 495,695 0 0
SVB FINANCIAL GROUP COM 78486Q101 16,613 29,695 SH   DFND 1 29,695 0 0
SYNEOS HEALTH INC CL A 87166B102 6,589 81,401 SH   DFND 1 81,401 0 0
SYNOPSYS INC COM 871607107 89,309 267,979 SH   DFND 1 267,979 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 9,535 91,458 SH   DFND 2 91,458 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 4,800 31,224 SH   DFND 1 31,224 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 1,764 15,173 SH   DFND 1 15,173 0 0
TE CONNECTIVITY LTD SHS H84989104 49,006 374,152 SH   DFND 1 374,152 0 0
TECK RESOURCES LTD CL B 878742204 7,920 196,081 SH   DFND 1 196,081 0 0
TELEFLEX INCORPORATED COM 879369106 5,222 14,718 SH   DFND 1 14,718 0 0
TENABLE HLDGS INC COM 88025T102 84,425 1,460,900 SH   DFND 1 1,460,900 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 14,183 165,000 SH   DFND 1 165,000 0 0
TESLA INC COM 88160R101 109,988 102,068 SH   DFND 1 102,068 0 0
TEXAS INSTRS INC COM 882508104 1,802 9,822 SH   DFND 1 9,822 0 0
THE LION ELECTRIC COMPANY COMMON STOCK 536221104 168 20,010 SH   DFND 1 20,010 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 14,050 23,788 SH   DFND 1 23,788 0 0
T-MOBILE US INC COM 872590104 37,654 293,371 SH   DFND 1 293,371 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 27,953 315,708 SH   DFND 1 315,708 0 0
TRANE TECHNOLOGIES PLC SHS G8994E103 594 3,892 SH   DFND 1 3,892 0 0
TRAVELERS COMPANIES INC COM 89417E109 122,279 669,178 SH   DFND 1 669,178 0 0
TRIMBLE INC COM 896239100 1,134 15,713 SH   DFND 1 15,713 0 0
TRIPADVISOR INC COM 896945201 104,951 3,869,871 SH   DFND 1 3,869,871 0 0
TRUPANION INC COM 898202106 22,280 250,000 SH   DFND 1 250,000 0 0
TUSIMPLE HLDGS INC CL A 90089L108 274 22,498 SH   DFND 1 22,498 0 0
TWILIO INC CL A 90138F102 91,453 554,902 SH   DFND 1 554,902 0 0
TWITTER INC NOTE 3/1 90184LAN2 29,135 34,500,000 SH   DFND 1 34,500,000 0 0
TWITTER INC COM 90184L102 20,803 537,692 SH   DFND 1 537,692 0 0
UBER TECHNOLOGIES INC COM 90353T100 14,371 402,785 SH   DFND 1 402,785 0 0
UBS GROUP AG SHS H42097107 14,835 780,579 SH   DFND 1 780,579 0 0
UIPATH INC CL A 90364P105 5,565 257,772 SH   DFND 1 257,772 0 0
UNION PAC CORP COM 907818108 11,208 41,022 SH   DFND 1 41,022 0 0
UNITED RENTALS INC COM 911363109 37,323 105,072 SH   DFND 1 105,072 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 66,988 373,380 SH   DFND 1 373,380 0 0
UNITEDHEALTH GROUP INC COM 91324P102 91,657 179,730 SH   DFND 1 179,730 0 0
UNITY SOFTWARE INC COM 91332U101 100,267 1,010,656 SH   DFND 1 1,010,656 0 0
UPSTART HLDGS INC COM 91680M107 4,511 41,350 SH   DFND 1 41,350 0 0
US FOODS HLDG CORP COM 912008109 33,243 883,410 SH   DFND 1 883,410 0 0
VAIL RESORTS INC NOTE 1/0 91879QAN9 37,479 38,500,000 SH   DFND 1 38,500,000 0 0
VALENS SEMICONDUCTOR LTD ORDINARY SHARES M9607U115 54 10,359 SH   DFND 1 10,359 0 0
VELODYNE LIDAR INC COM 92259F101 53 20,747 SH   DFND 1 20,747 0 0
VEONEER INC COM 92336X109 437 11,828 SH   DFND 1 11,828 0 0
VERICEL CORP COM 92346J108 337 8,814 SH   DFND 1 8,814 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 78,364 300,280 SH   DFND 1 300,280 0 0
VERTICAL AEROSPACE LTD ORD SHS G9471C107 154 22,086 SH   DFND 1 22,086 0 0
VERTIV HOLDINGS CO COM CL A 92537N108 3,745 267,514 SH   DFND 1 267,514 0 0
VICOR CORP COM 925815102 242 3,427 SH   DFND 1 3,427 0 0
VISA INC COM CL A 92826C839 38,146 172,008 SH   DFND 1 172,008 0 0
VISHAY INTERTECHNOLOGY INC COM 928298108 223 11,398 SH   DFND 1 11,398 0 0
VISTEON CORP COM NEW 92839U206 465 4,257 SH   DFND 1 4,257 0 0
VMWARE INC CL A COM 928563402 769 6,756 SH   DFND 1 6,756 0 0
VOLTA INC COM CL A 92873V102 91 29,828 SH   DFND 1 29,828 0 0
WALLBOX NV SHS CL A N94209108 323 25,330 SH   DFND 1 25,330 0 0
WEBSTER FINL CORP COM 947890109 7,857 140,012 SH   DFND 1 140,012 0 0
WELLS FARGO CO NEW COM 949746101 18,712 386,134 SH   DFND 1 386,134 0 0
WESTERN ALLIANCE BANCORP COM 957638109 13,068 157,788 SH   DFND 1 157,788 0 0
WOLFSPEED INC COM 977852102 1,874 16,455 SH   DFND 1 16,455 0 0
WORKDAY INC CL A 98138H101 65,877 275,106 SH   DFND 1 275,106 0 0
WORKHORSE GROUP INC COM NEW 98138J206 82 16,473 SH   DFND 1 16,473 0 0
XENON PHARMACEUTICALS INC COM 98420N105 66,950 2,190,059 SH   DFND 1 2,190,059 0 0
XL FLEET CORP COM CL A 9837FR100 29 14,724 SH   DFND 1 14,724 0 0
XOS INC COMMON STOCK 98423B108 51 17,204 SH   DFND 1 17,204 0 0
XPENG INC ADS 98422D105 6,377 231,140 SH   DFND 1 231,140 0 0
Y-MABS THERAPEUTICS INC COM 984241109 34,187 2,877,671 SH   DFND 1 2,877,671 0 0
ZAI LAB LTD ADR 98887Q104 5,822 132,382 SH   DFND 1 132,382 0 0
ZENDESK INC COM 98936J101 148,311 1,232,949 SH   DFND 1 1,232,949 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 17,041 369,329 SH   DFND 1 369,329 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 18,537 144,936 SH   DFND 1 144,936 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 61,701 526,327 SH   DFND 1 526,327 0 0
ZUORA INC COM CL A 98983V106 6,127 409,021 SH   DFND 1 409,021 0 0