Note 11 - Stock Option Plans - Schedule of Stock Option Activity (Details) - USD ($)	6 Months Ended	12 Months Ended
	Jun. 30, 2023	Dec. 31, 2022
Outstanding, options (in shares)	7,095,462
Outstanding options, weighted average exercise price (in dollars per share)	$ 1.99
Outstanding, weighted average remaining contractual life (Year)	6 years 7 months 2 days	5 years 9 months 14 days
Aggregate intrinsic value, outstanding	$ 1,660,330	$ 109,891
Granted, options (in shares)	2,911,750
Granted, weighted average exercise price (in dollars per share)	$ 0.57
Forfeited, options (in shares)	(33,847)
Forfeited, weighted average exercise price (in dollars per share)	$ 2.26
Exercised, options (in shares)	(3,500)
Exercised, weighted average exercise price (in dollars per share)	$ 0.54
Expired, options (in shares)	(32,076)
Expired, weighted average exercise price (in dollars per share)	$ 4.90
Outstanding, options (in shares)	9,937,789	7,095,462
Outstanding options, weighted average exercise price (in dollars per share)	$ 1.56	$ 1.99
Options vested and exercisable, options (in shares)	4,539,909
Options vested and exercisable, weighted average exercise price (in dollars per share)	$ 2.01
Options vested and exercisable, weighted average remaining contractual life (Year)	3 years 2 months 23 days
Aggregate Intrinsic Value, Options vested and exercisable	$ 637,770