<SEC-DOCUMENT>0001104659-22-131391-index.html : 20221230
<SEC-HEADER>0001104659-22-131391.hdr.sgml : 20221230
<ACCEPTANCE-DATETIME>20221230165708
ACCESSION NUMBER:		0001104659-22-131391
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20221230
DATE AS OF CHANGE:		20221230
GROUP MEMBERS:		PETER KOLCHINSKY
GROUP MEMBERS:		RA CAPITAL HEALTHCARE FUND, L.P.
GROUP MEMBERS:		RAJEEV SHAH

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Achilles Therapeutics plc
		CENTRAL INDEX KEY:			0001830749
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-92487
		FILM NUMBER:		221502460

	BUSINESS ADDRESS:	
		STREET 1:		245 HAMMERSMITH ROAD
		CITY:			LONDON
		STATE:			X0
		ZIP:			W6 8PW
		BUSINESS PHONE:		44 (0)20 8154 4600

	MAIL ADDRESS:	
		STREET 1:		245 HAMMERSMITH ROAD
		CITY:			LONDON
		STATE:			X0
		ZIP:			W6 8PW

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Achilles Therapeutics Ltd
		DATE OF NAME CHANGE:	20201030

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RA CAPITAL MANAGEMENT, L.P.
		CENTRAL INDEX KEY:			0001346824
		IRS NUMBER:				830406777
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		200 BERKELEY STREET, 18TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		617-778-2500

	MAIL ADDRESS:	
		STREET 1:		200 BERKELEY STREET, 18TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	RA CAPITAL MANAGEMENT, LLC
		DATE OF NAME CHANGE:	20051213
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>tm2233772d1_sc13da.htm
<DESCRIPTION>SC 13D/A
<TEXT>
Document 1 - file: tm2233772d1_sc13da.htm

</DOCUMENT>
</SEC-DOCUMENT>