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Consolidated statements of cash flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (69,665) $ (71,176) $ (61,099)
Adjustments to reconcile net loss to net cash used in operating activities      
Depreciation and amortization 4,713 3,690 3,288
Loss on disposal of property and equipment 2 (10) 156
Gain on termination of operating lease (45)    
Loss on impairment 16 7,446  
Changes in right of use assets and operating lease liabilities, net (231) (601) (18)
Non-cash loss on foreign currency remeasurement (5) 50 3
Non-cash share-based compensation 6,357 7,022 6,317
Changes in operating assets and liabilities      
Prepaid expenses and other current assets 10,109 (6,845) (9,771)
Accounts payable 257 1,907 (2,572)
Income taxes payable (326) 326 (7)
Accrued expenses and other liabilities (801) (1,114) 4,937
Other long-term liability 33 321 47
Deferred tax assets 210 (225) (22)
Other assets 927 (326) (543)
Net cash used in operating activities (48,449) (59,535) (59,284)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of property and equipment (1,100) (7,512) (7,634)
Net cash used in investing activities (1,100) (7,512) (7,634)
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from the issuance of shares 9 1  
Issuance of ADRs in initial public offering, net of issuance costs under the employee share purchase plan     160,755
Net cash provided by financing activities 9 1 160,755
Effect of exchange rate changes on cash equivalents and restricted cash 7,741 (25,935) (5,334)
Net (decrease) increase in cash (41,799) (92,981) 88,503
Cash, cash equivalents and restricted cash, beginning of year 173,371 266,352 177,849
Cash, cash equivalents and restricted cash, end of year 131,572 173,371 266,352
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:      
Right of use assets obtained in exchange for new operating lease liabilities 2,108 2,111 314
Right of use assets terminated in exchange for operating lease liabilities, net (1,916)    
Property and equipment purchases in accrued expenses 540 649 726
Cash paid for income taxes 626 76 8
Cash and cash equivalents 131,539 173,338 266,319
Restricted cash $ 33 $ 33 $ 33