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Investments and Equity Method Investments - Schedule of (Losses) Gains on Investments and Equity Method Investments (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Net Investment Income [Line Items]      
(Loss) gain on investments $ (11,543) $ (3,733) $ (27,200)
Loss on equity method investments (77,284) (396) (27,533)
Synlogic, Inc. common stock [Member]      
Net Investment Income [Line Items]      
(Loss) gain on investments 1,649 (2,663) (19,403)
Synlogic, Inc. warrants [Member]      
Net Investment Income [Line Items]      
(Loss) gain on investments 662 (1,070) (7,797)
Cronos Group Inc. [Member]      
Net Investment Income [Line Items]      
(Loss) gain on investments (13,854)
Joyn Bio, LLC [Member]      
Net Investment Income [Line Items]      
Loss on equity method investments (17,230) (396) (1,730)
Allonnia, LLC [Member]      
Net Investment Income [Line Items]      
Loss on equity method investments (12,698) (24,480)
Arcaea LLC [Member]      
Net Investment Income [Line Items]      
Loss on equity method investments (47,356)
Glycosyn, LLC [Member]      
Net Investment Income [Line Items]      
Loss on equity method investments $ (1,323)