Free Writing Prospectus dated March 5, 2021 Filed pursuant to Rule 433Relating to the Preliminary Prospectus March 5, 2021Registration Statement No. 333-253257 PIONEERING MEAT 2 . 0 MARCH 2021 © 2021 ALL RIGHTS RESERVED

This presentation and oral statements made regarding the subject of this presentation contain “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties. Such statements include, without limitation, references to the MeaTech 3D Ltd.’s (the “Company’s”) predictions or expectations of future business or financial performance and its goals and objectives for future operations, financial and business trends, performances, strategies or expectations. In some cases, you can identify forward-looking statements by the words “may,” “might,” “could,” “would,” “should,” “expect,” “intend,” “plan,” “objective,” “anticipate,” “believe,” “estimate,” “predict,” “potential,” “continue” and “ongoing,” or the negative of these terms, or other comparable terminology intended to identify statements about the future. These forward-looking statements may not materialize, in whole or in part, or may materialize differently than expected, or may be affected by factors that cannot be assessed in advance. We may not actually achieve the plans, intentions or expectations disclosed in our forward- looking statements, and you should not place undue reliance on our forward looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in the forward-looking statements we make. You are cautioned not to place undue reliance on forward-looking statements. Except as otherwise indicated, the forward-looking statements contained in this presentation speak only as of the date of this presentation and the Company undertakes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.This presentation includes statistical, market and industry data and forecasts which we obtained f rom publicly available information and independent industry publications and reports that we believe to be reliable sources. These publicly available industry publications and reports generally state that they obtain their information f rom sources that they believe to be reliable, but they do not guarantee the accuracy or completeness of the information. Although we are responsible for all of the disclosures contained in this presentation, including such statistical, market and industry data, we have not independently verif iedany of the data f rom third-party sources, nor have we ascertained the underlying economic assumptions relied upon therein. In addition, while we believe the market opportunity information included in this presentation is generally reliable and is based on reasonable assumptions, the industry in which we operate is subject to a high degree of uncertainty and risk due to a variety of important factors that could cause results to differ materially from those expressedintheestimatesmadebythirdpartiesandbyus.This presentation highlights basic information about us and the offering. Because it is a summary, it does not contain all of the information that you should consider before investing. This offering may only be made by means of a prospectus.We have filed a registration statement on Form F-1 (File No. 333-253257), including a preliminary prospectus, dated March 5, 2021 (the “Preliminary Prospectus”) with the SEC for the offering to which this communication relates. The registration statement has not yet become effective. Before you invest, you should read that registration statement, the Preliminary Prospectus and the final prospectus (when available) for more complete information about the Company and this offering. You may retrieve copies of these documents for free on the SEC’s website at https://www.sec.gov. Alternatively, copies of the Preliminary Prospectus and the final prospectus, when available, may be obtained fromH.C. Wainwright & Co., LLC, 430 Park Avenue, 3rd Floor, New York, New York 10022, by phone at (646) 975-6996 or by email at placements@hcwco.com. 2 DISCLAIMERS © 2021 ALL RIGHTS RESERVED

3 CONVENTIONAL - MEAT 1.0 RESOURCE-INTENSIVE INPUTS AND COSTLY ENVIRONMENTAL OUTPUTS W A TER RESOURCES 8 % of global f reshwater supply dedicated toraising livestock. Source: Food and Agriculture Organization of the United Nations ; Our World in Data MEA T P RODUC T SIn 2018 , approximately 72 billion animals wereslaughtered. L AND & FEED 33 % of croplands dedicated for animal feed. Concerns regarding anti-biotic and hormone use. LI V ES T OCK INP U T S O UT P UT S EMISSIONS 18% of atmospheric greenhouse gases, in addition toeffluent and runoff. © 2021 ALL RIGHTS RESERVED

4 CELLULAR AGRICULTURE - MEAT 2 . 0 RADICALLY MORE SUSTAINABLE: SLAUGHTER-FREE AND REDUCED EMISSIONS INP U T S O UT P UT S F A T CELL SStem cells are differentiated intofat cells. Y CLEAN ENERG S TEM CELL S & CELL MEDIA Eff icient use of cell media. B IOREA C T O R S MUSCLE CELL SStem cells are differentiated intomuscle cells. © 2021 ALL RIGHTS RESERVED

5 MEAT 2 . 0POTENTIAL ADVANTAGES FOR THE MEAT INDUSTRY SUSTAINABILITY: Cleaner, more recyclable inputs and lower emissions. SUPPLY CHAIN: Shortened and simplified by producing anywhere.FOOD SAFETY & SECURITY: Clean production environment, local exponential agriculture. 2 . 0 PRODUCTS : New ingredients and product categories including potentially healthier products. The above illustration depicts our current expectations for the development of our technologies and processes. © 2021 ALL RIGHTS RESERVED

6 CURRENT MEAT ALTERNATIVES LANDSCAPE DEMAND SUPPORTED BY STRONG CONSUMER SUPPORT EMERGING TECHNOLOGY ADVANCEMENT ORGANOLEPTIC PROPERTIES LEGEND Plant Based Cultured Meat + Hybrid Meat + + TO DA Y NASCENT 3D Printed Cultured Meat + + 3d bioprinter NASCENT © 2021 ALL RIGHTS RESERVED

7 CULTURED MEAT FORECAST THE FASTEST GROWING ALTERNATIVE PROTEIN SEGMENT COMPARED TO CONVENTIONAL AND PLANT-BASED MEAT P L ANT BASED C ON V ENTIONAL MEAT C U LT URED MEAT Source: A.T. Kearney analysis in billions $US +3% © 2021 ALL RIGHTS RESERVED

9 FACTORY OF THE FUTURE A VISION OF A MULTI-SPECIES, MULTI-PRODUCT, HIGH-VOLUME CULTURED MEAT PRODUCTION PLANT The above illustration depicts our current expectations for the development of our technologies and processes. © 2021 ALL RIGHTS RESERVED

10 DEVELOPING HIGH THROUGHPUT 3D TISSUE ENGINEERINGPLANNED TISSUE PRINTING & INCUBATION Scaffold materialsBio-ink formulationsSoftware development SCALING UP CELL-BASED PROCESSPLANNED BIOREACTOR SYSTEMS & PROCESSES Multi-species biomass production technologies:FatMuscle MEATECH’ S CORE R&D Note: These images are computer generated and represent future expectations. © 2021 ALL RIGHTS RESERVED

11 CELL COLLECTION GROWING CELLS DIFFERENTIATING CELLSUpon reaching sufficient cell quantities, stem cells are differentiated into fat and muscle cells. GROUND PRODUCTS Cell lines are developed to reliably express particular characteristics. Stem cells are transferred to bioreactors for exponential growth under ideal conditions. Unstructured cell-based products (beef or chicken): fat, ground, hybrid or formed. MEATECH’ S CELL-BASED PROCESS VISION PRODUCING CULTURED FAT AND MUSCLE CELLS © 2021 ALL RIGHTS RESERVED

12 MEATECH'S CULTURED STEAK VISION BIO-INKS 3D BIOPRINTING INCUBATION STRUCTURED MEAT Bio-inks formulated from our cell lines and unique scaffolding materials are loaded into our 3D bioprinter. Bio-inks are accurately printed to assemble cells as they would be found in a conventional cut of muscle. Printed product is incubated to mature and form tissue. Produced in fraction of time required to achieve same cut via conventional means. A FLEXIBLE MANUFACTURING PROCESS FOR 3D PRINTED TISSUE © 2021 ALL RIGHTS RESERVED

13 TARGETING ALL CULTURED MEAT CATEGORIES ORGANOLEPTIC PROPERTIES LEGEND Plant Based Cultured Meat + 3D Printed Cultured Meat + + 3d bioprinter Competitors Hybrid Meat + + Nestle Morning Star Cubiq Foods Mosa Meat Memphis Meats Peace Of Meat Aleph Farms Eat Just Inc.FutureMeat Kellogg's Super Meat Beyond Meat Impossible Foods COMPETITIVE LANDSCAPE TECHNOLOGY ADVANCEMENT © 2021 ALL RIGHTS RESERVED

15 WE ANTICIPATE SCALING OUR TECHNOLOGY FROM THE LAB TO AN INDUSTRIAL PROCESS FOR LARGE-SCALE PRODUCTION OF MEAT 2 . 0 PRODUCTS Key criteria are:Capabilities of the cell line being used.Formulation of the cell-culturing media and reduction in costs.Management of the bioreactor hardware. In 2020, MeaTech employed lab-scale bioreactors to produce muscle and fat cells to print a uniform thin, slaughter free meattissue. Lab scale Pilot plant USE OF FUNDS:UPSCALING PATHWAY Pilot Manufacturingplant © 2021 ALL RIGHTS RESERVED

16 MEATECH GROUP MAMMALIAN A V IAN A QU A C U L T URE C URRENT S TRA TE GY F OR THE F A C T OR Y OF THE FU T URE *Under considerationOther Species : L amb , P or kEcosystem technologies : Gr o w th F a c t or De v elopm ent & Gr o w th F a c t or P r oduc tion SP E CIES TY P E MEA TE CH GROUP C OMP ANY Exploring potential avenues for expansion HY BRID P RODUC T S HY BRID P RODUC T S GROUND MEA T P ROCESSED MEA T P ROCESSED MEA T S TRUC T URED 3D P RINTED S TRUC T URED 3D P RINTED GROUND MEA T F AT CELL S F AT CELL S MUSCLE CELL S MUSCLE CELL S A MeaTech company*acquired Feb 2020 TARGETING A BROAD RANGE OF CELL TYPES AND CULTURED PRODUCTS THROUGH R&D AND ACQUISITIONS © 2021 ALL RIGHTS RESERVED

17 MEATECH'S ACQUISITION: INTRODUCING PEACE OF MEAT A preeminent cultured avian technology company POM is a B2B company developing cultured fat as a tasty and texturing ingredient.POM is focused on improving the taste, texture and nutritional value of plant-based and cell-based proteins. We believe adding 10-25% of POM cultured fat and cultured meat to a plant-based protein designed to result in meatier flavors and mouthfeel.POM cultured fat is designed to be antibiotic free and provide enhanced fatty acid profiles and personalized nutritional profiles. Peace of Meat's public tasting of hybrid products. © 2021 ALL RIGHTS RESERVED

18 B2B ANTICIPATED BUSINESS MODEL LICENSED PRODUCTIONFACILITIES FOOD TECHNOLOGY SERVICES & RAW MATERIALS ENGINEERING BUILD & SERVICE CELLPRODUCTION TISSUEENGINEERING MEATECH OFFERING REVENUE STREAMS SUPPORT SERVICE REVENUES © 2021 ALL RIGHTS RESERVED

20 SHARON FIMACEO & CO-FOUNDERSharon is an entrepreneur with over 20 years of experience in the printing industry. Sharon was a co-founder and the CTO of Nano Dimension (NNDM) andspearheaded the development of a complete desk-top 3D printing system for multilayer PCBs. Prior to NNDM, Sharon was the R&D Integration manager at XJet and an R&D team leader at HP Indigo. OMRI SCHANINCOO & CO-FOUNDEROmri, a co-Founder of MeaTech and COO focused on supporting cross-functional teams to see R&D achieve commercialization. Omri has a successful history of entrepreneurship in a variety ofhigh-tech sectors including medical devices and medication. Omri served as Deputy Naval Commander of a missile ship in the IDF. GUY HEFERCFOGuy has broad international business experience with a successful track record of transaction generation and execution. Prior to joining MeaTech Guy was the CFO of a tech-focused holding company. Prior to thatGuy was an investment banker for Leumi bank in Israel and Barclays investment Banking Division in Israel and in the UK. Guy holds a BA in Accounting & Economics from Tel Aviv University. SIMON FRIEDHEAD OF BUSINESSSimon is a seasoned international executive with experience covering tech, retail, FMCG, finance and strategy consulting. Co-founder, CBO and US President of Nano Dimension Simon is a serial entrpreneur having co-founded a whisky distillery and boutique behavioral economics consulting firm. He holds an MBAfrom SDA Bocconi and an M.Sc from Oxford University. OUR LEADERSHIP © 2021 ALL RIGHTS RESERVED

21 PEACE OF MEAT - TEAM DAVID BRANDESCO-FOUNDER & MANAGINGDIRECTORBefore co-founding POM, David amassed a decade of experience in consumer and food systems with Procter & Gamble, McKinsey & Company, and Migros. David focuses on generating business opportunities whilst reducing human environmental impact, starting with the highest impact opportunity - our food system. DR. PAUL MOZDZIAKCSODr. Paul Mozdziak serves as Physiology Professor at North Carolina State University. His work focuses on cellular and molecular mechanisms of cell growth.Internationally recognized as an expert in cell culture technology, Paul authored more than 100 peer- reviewed publications, has almost 30years’ experience culturing vertebrate cells.. DIRK VON HEINRICHSHORSTCO-FOUNDER & CEODirk is a co-founder and CEO of Peace of Meat, the first cultured meat company in Belgium and the driving force behind building Peace of Meat's vision of industrial scale biomass production facilities. Constantly driven by technological innovations, Dirk has 20 yearsof experience as an IT engineer, blockchain expert and coder. © 2021 ALL RIGHTS RESERVED

22 PROF. SHLOMO MAGDASSICHEMISTRYProf. Shlomo Magdassi is a Professor of Chemistry at the Hebrew University of Jerusalem. His research focuses on colloid science, particularly on the formation,formulation, and application of novel micro and nanoparticles. AMB. DANNY AYALONDIRECTORFormer Israeli Ambassador to the United States and Deputy Minister of Foreign Affairs, Member of Knesset and advisor to three prime ministers. Co-founder and Chairman of Silver Road Capital Ltd. PROF. TAL DVIRBIOLOGYProf. Dvir obtained his degrees in Biotechnology Engineering from Ben-Gurion University. Prof. Dvir continued his postdoctoral studies in the laboratory of Prof. Robert Langer at MIT. Prof. Dvir established the Laboratory for Tissue Engineeringand Regenerative Medicine at Tel Aviv University. OUR ADVISORS STEVEN H. LAVINCHAIRMANMr. Lavin serves as Vice Chairman of OSI Group, LLC, a global supplier of value-added food and meat products. Mr. Lavin is the President of Lavin & Gedville, a boutique law firm. © 2021 ALL RIGHTS RESERVED

23 A YEAR OF TRIUMPH MEATECH’ S ACHIEVEMENTS OVER THE LAST TWELVE MONTHS BIOLOGYSuccessful differentiation of stem cells to fat cells. Successful development of lower cost growth medium. Successful differentiation of stem cells to muscle cells.Growth of chicken cells in suspension. PRINTINGFirst printing of a uniform thin, slaughter free meat tissue.Bioprinting cultured beef fat structure. BUSINESSMeaTech acquired cultured fat pioneer ‘Peace of Meat’. © 2021 ALL RIGHTS RESERVED

24 SUMMARY A large rapidly growing alternative protein marketWorld class R&D team and scientif ic advisorsEmerging technology leader in cultured fat production & 3Dbioprinting of meatA planned B2B business modeltargeting rapid commercialization The below illustration depicts our current expectations for the development of our technologies and processes. © 2021 ALL RIGHTS RESERVED

26 IMPACT OF SUSTAINABILITY WATER USE CO2 EMISSIONS LAND USE 16,000 LITERS 14 KG 160 M2 CONVENTIONALMEAT (1KG) 2,500 LITERS 3 KG 1.6 M2 CULTUREDMEAT (1KG) Source: CB Insights, Water Footprint Network, Business Insider, Forbes, Expert Interviews. CONVENTIONAL FARMING COMPARED TO CULTURED MEAT PRODUCTION © 2021 ALL RIGHTS RESERVED

27 MEATECH'S INTELLECTUAL PROPERTY PATENT APPLICATIONS SUBMITTED BUT NOT YET GRANTED: Cultured Edible Meat Fabrication Using Bioprinting © 2021 ALL RIGHTS RESERVED Harvesting Bovine Embryonic Inner Cell Mass Physical Manipulation of Cultured Tissue Bioprinter Print Head Growth Support For Cell Culture Bovine Umbilical Cord Stem Cells As Feeder Layer