Stockholders' equity - Summary of Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Options Outstanding, Beginning Balance, Number of Shares	2,736,918	1,086,902
Exercised, Number of Shares	0	0
Forfeiture, Number of Shares	(371,439)	(50,387)
Expired, Number of Shares	(112,367)	(17,797)
Stock Options Outstanding, Ending Balance, Number of Shares	6,273,507	2,736,918	1,086,902
Vested and expected to vest, Number of Shares	6,273,507
Equity Option
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted, Number of Shares	4,020,395	1,718,200
Exercisable, Number of Shares	1,429,449
Outstanding, Beginning Balance, Weighted-Average Exercise Price per Share	$ 13.82	$ 26.76
Granted, Weighted-Average Exercise Price per Share	3.74	6.35
Exercised, Weighted average exercise price per option	0	0
Forfeited, Weighted average exercise price per option	7.2	21.64
Expired, Weighted average exercise price per option	20.96	40
Exercisable, Weighted average exercise price per option	14.98
Outstanding, Ending Balance, Weighted-Average Exercise Price per Share | $ / shares	7.62	$ 13.82	$ 26.76
Vested and expected to vest, Weighted-Average Exercise Price per Share	$ 7.62
Outstanding, Weighted-Average Remaining Contractual Term (years)	8 years 7 months 20 days	8 years 9 months 25 days	9 years 2 months 19 days
Vested and expected to vest, Weighted-Average Remaining Contractual Term (years)	8 years 7 months 20 days
Exercisable, Weighted-Average Remaining Contractual Term (years)	7 years 9 months
Outstanding, Aggregate Intrinsic Value	$ 3,636,148	$ 991,495
Outstanding, Aggregate Intrinsic Value	74,680	$ 3,636,148	$ 991,495
Vested and expected to vest, Aggregate Intrinsic Value	74,680
Exercisable, Aggregate Intrinsic	$ 2,007