Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Collaboration and other revenue	$ 0	$ 250
Operating expenses:
Research and development expense	79,347	58,274
General and administrative expense	28,793	38,416
Total operating expenses	108,140	96,690
Loss from operations	(108,140)	(96,440)
Other income (expense):
Interest income	1,648	350
interest expense	0	(3)
Gain on extinguishment of long-term debt	0	690
Other income (expense)	10	1
Total other income (expense)	1,658	1,038
Consolidated net loss and comprehensive loss	$ (106,482)	$ (95,402)
Net loss per common share, basic	$ (2.74)	$ (2.76)
Net loss per common share, diluted	$ (2.74)	$ (2.76)
Weighted-average shares of common stock outstanding, basic	38,927,268	34,561,245
Weighted-average shares of common stock outstanding, diluted	38,927,268	34,561,245