Balance sheet details - Schedule of Property and Equipment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Property And Equipment [Line Items]
Property and equipment, gross	$ 8,092	$ 7,933
Less accumulated depreciation and amortization	(5,364)	(4,257)
Total	2,728	3,676
Furniture Fixtures and Office Equipment
Property And Equipment [Line Items]
Property and equipment, gross	$ 2,140	$ 2,123
Laboratory Equipment
Property And Equipment [Line Items]
Property and equipment useful life	5 years	5 years
Property and equipment, gross	$ 2,265	$ 2,123
Leasehold Improvements
Property And Equipment [Line Items]
Property and equipment, gross	$ 3,687	$ 3,687
Minimum | Furniture Fixtures and Office Equipment
Property And Equipment [Line Items]
Property and equipment useful life	3 years	3 years
Minimum | Leasehold Improvements
Property And Equipment [Line Items]
Property and equipment useful life	2 years	2 years
Maximum | Furniture Fixtures and Office Equipment
Property And Equipment [Line Items]
Property and equipment useful life	7 years	7 years
Maximum | Leasehold Improvements
Property And Equipment [Line Items]
Property and equipment useful life	3 years	3 years