Unaudited Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Income Statement [Abstract]
Collaboration and other revenue				$ 250
Operating expenses:
Research and development expense	19,839	16,553	57,473	41,826
General and administrative expense	6,340	7,142	22,107	31,376
Total operating expenses	26,179	23,695	79,580	73,202
Loss from operations	(26,179)	(23,695)	(79,580)	(72,952)
Other income (expense):
Interest income	370	76	601	254
Interest expense				(3)
Gain on extinguishment of long-term debt		690		690
Other income (expense)	30	(1)	40	(1)
Total other income (expense)	400	765	641	940
Consolidated net loss and comprehensive loss	$ (25,779)	$ (22,930)	$ (78,939)	$ (72,012)
Net loss per common share, basic	$ (0.69)	$ (0.68)	$ (2.11)	$ (2.13)
Net loss per common share, diluted	$ (0.69)	$ (0.68)	$ (2.11)	$ (2.13)
Weighted-average shares of common stock outstanding, basic	37,516,769	33,909,460	37,420,531	33,751,558
Weighted-average shares of common stock outstanding, diluted	37,516,769	33,909,460	37,420,531	33,751,558