Related Party Transactions - Additional Information (Details) - USD ($)		3 Months Ended		6 Months Ended
	Mar. 18, 2021	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020
Related Party Transaction [Line Items]
Interest expense related party		$ 0	$ 79,000	$ 0	$ 138,000
Related party transaction, terms and manner of settlement				On March 18, 2021, the Company and Carolyn Anderson Short, its co-founder and former Chief of Intellectual Property & Strategy, mutually agreed that Ms. Short would depart the Company on May 31, 2021 following an agreed upon transition period. The Transition Agreement provides for the following severance benefits in exchange for a release of claims by Ms. Short: (i) a lump sum payment equal to eighteen (18) months of Ms. Short’s current base salary, (ii) a payment at her targeted bonus rate for 2021, pro-rated to the separation date, and (iii) accelerated full vesting of her equity awards including 7,747 stock options and 138,461 restricted stock units. The modification of these equity awards resulted in an incremental fair value of $7.0 million which was recognized on a straight-line basis over the transition service period. For the three and six months ended June 30, 2021, the Company recognized $0.8 million and $1.0 million, respectively, related to the lump sum salary payment and target bonus. The Company also recognized non-cash stock-based compensation charges of $8.4 million and $9.4 million related to the modified equity awards for the three and six months ended June 30, 2021, respectively. No unrecognized stock-based compensation remained as of June 30, 2021.
Non-cash stock-based compensation charges		12,298,000	0	$ 16,941,000	0
Ms. Short
Related Party Transaction [Line Items]
Number of accelerated full vesting equity awards including stock options	7,747
Number of accelerated full vesting equity awards including restricted stock units	138,461
Incremental Fair Value				7,000,000.0
Expense related to Lump Sum Salary Payment and Target Bonus		800,000		1,000,000.0
Non-cash stock-based compensation charges		8,400,000		9,400,000
Unrecognized stock-based compensation		$ 0		$ 0
Biotech Investment Group II LLC
Related Party Transaction [Line Items]
Interest expense related party			20,000		40,000
Debt instrument settled date				2020-07
Dr. Jay Short and Carolyn Anderson Short
Related Party Transaction [Line Items]
Interest expense related party			$ 59,000		$ 98,000
Debt instrument settled date				2020-07