<SEC-DOCUMENT>0001819113-23-000014-index.html : 20230309
<SEC-HEADER>0001819113-23-000014.hdr.sgml : 20230309
<ACCEPTANCE-DATETIME>20230309163659
ACCESSION NUMBER:		0001819113-23-000014
CONFORMED SUBMISSION TYPE:	ARS
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20221231
FILED AS OF DATE:		20230309
DATE AS OF CHANGE:		20230309
EFFECTIVENESS DATE:		20230309

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Science 37 Holdings, Inc.
		CENTRAL INDEX KEY:			0001819113
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				844278203
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		ARS
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39727
		FILM NUMBER:		23720259

	BUSINESS ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709
		BUSINESS PHONE:		(984) 377-3737

	MAIL ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Lifesci Acquisition II Corp.
		DATE OF NAME CHANGE:	20200723
</SEC-HEADER>
<DOCUMENT>
<TYPE>ARS
<SEQUENCE>1
<FILENAME>snce12312210-kannualreport.pdf
<DESCRIPTION>ARS
<TEXT>
Document 1 - file: snce12312210-kannualreport.pdf

</DOCUMENT>
</SEC-DOCUMENT>