<SEC-DOCUMENT>0001140361-23-049957-index.html : 20231027
<SEC-HEADER>0001140361-23-049957.hdr.sgml : 20231027
<ACCEPTANCE-DATETIME>20231027161125
ACCESSION NUMBER:		0001140361-23-049957
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		5
CONFORMED PERIOD OF REPORT:	20231129
FILED AS OF DATE:		20231027
DATE AS OF CHANGE:		20231027

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Science 37 Holdings, Inc.
		CENTRAL INDEX KEY:			0001819113
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				844278203
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39727
		FILM NUMBER:		231355634

	BUSINESS ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709
		BUSINESS PHONE:		(984) 377-3737

	MAIL ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Lifesci Acquisition II Corp.
		DATE OF NAME CHANGE:	20200723
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>ny20010632x2_def14a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: ny20010632x2_def14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>logo_science37.jpg
<TEXT>
Document 2 - file: logo_science37.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>ny20010632x2_arrow.jpg
<TEXT>
Document 3 - file: ny20010632x2_arrow.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>ny20010632x2_pc-01.jpg
<TEXT>
Document 4 - file: ny20010632x2_pc-01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>ny20010632x2_pc-02.jpg
<TEXT>
Document 5 - file: ny20010632x2_pc-02.jpg

</DOCUMENT>
</SEC-DOCUMENT>