<SEC-DOCUMENT>0001104659-23-055021-index.html : 20230502
<SEC-HEADER>0001104659-23-055021.hdr.sgml : 20230502
<ACCEPTANCE-DATETIME>20230502161117
ACCESSION NUMBER:		0001104659-23-055021
CONFORMED SUBMISSION TYPE:	SC TO-I/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230502
DATE AS OF CHANGE:		20230502

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Science 37 Holdings, Inc.
		CENTRAL INDEX KEY:			0001819113
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				844278203
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC TO-I/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91857
		FILM NUMBER:		23879066

	BUSINESS ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709
		BUSINESS PHONE:		(984) 377-3737

	MAIL ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Lifesci Acquisition II Corp.
		DATE OF NAME CHANGE:	20200723

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Science 37 Holdings, Inc.
		CENTRAL INDEX KEY:			0001819113
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				844278203
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC TO-I/A

	BUSINESS ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709
		BUSINESS PHONE:		(984) 377-3737

	MAIL ADDRESS:	
		STREET 1:		800 PARK OFFICES DRIVE
		STREET 2:		SUITE 3606
		CITY:			RESEARCH TRIANGLE PARK
		STATE:			NC
		ZIP:			27709

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Lifesci Acquisition II Corp.
		DATE OF NAME CHANGE:	20200723
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC TO-I/A
<SEQUENCE>1
<FILENAME>tm2310996d5_sctoia.htm
<DESCRIPTION>SC TO-I/A
<TEXT>
Document 1 - file: tm2310996d5_sctoia.htm

</DOCUMENT>
</SEC-DOCUMENT>