Exhibit 107

Calculation of Filing Fee Tables

Form 424(b)(5)

(Form Type)

Dyne Therapeutics, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

	Security Type	Security Class Title	Fee Calculation  or Carry Forward Rule	Amount Registered(1)	Proposed Maximum  Offering Price Per Unit	Maximum Aggregate Offering Price	Fee Rate	Amount of Registration Fee(2)	Carry Forward  Form Type	Carry Forward  File Number	Carry Forward  Initial Effective Date	Filing Fee Previously Paid In Connection  with Unsold Securities to be Carried Forward
Newly Registered Securities
Fees to Be Paid	Equity	Common Stock, par  value $0.0001 per share	457(r)	12,075,000	$31.00	$374,325,000	0.00014760	$55,250.37	—	—	—	—
Fees Previously Paid	—	—	—	—	—	—	—	—	—	—	—	—
Carry Forward Securities
Carry Forward Securities	—	—	—	—	—	—	—	—	—	—	—	—
	Total Offering Amounts					$374,325,000		$55,250.37
	Total Fees Previously Paid							—	—
	Total Fee Offsets							—	—
	Net Fee Due							$55,250.37

(1) Includes 1,575,000 shares of common stock the underwriters have an option to purchase.

(2) Calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended (the “Securities Act”). The fee payable in connection with the offering pursuant to this prospectus supplement has been paid in accordance with Rule 456(b) under the Securities Act and represents deferred payment of the registration fees in connection with the Registrant’s Registration Statement on Form S-3 (Registration No. 333-277655) (the “Registration Statement”). This “Calculation of Filing Fee Tables” shall be deemed to update the “Calculation of Filing Fee Tables” filed as Exhibit 107 to the Registration Statement in accordance with Rules 456(b) and 457(r) under the Securities Act.