Income Taxes - Significant Components of Net Deferred Tax Assets (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets:
Stock-based compensation	$ 4,176	$ 2,333
Net operating loss carryforwards	59,998	51,500
Credit carryforwards	11,225	4,799
Fixed assets	564	705
Accrued expenses	4,682	5,205
Lease liability	8,264	8,916
R&D Capitalization	33,515	0
Total deferred tax assets	122,424	73,458
Valuation allowance	(113,622)	(63,546)	$ (21,899)
Total net deferred tax assets	8,802	9,912
Deferred tax liabilities:
Right of use asset	(8,802)	(9,912)
Total deferred tax liability	(8,802)	(9,912)
Total deferred tax assets (liabilities)	$ 0	$ 0