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Income Taxes - Reconciliation of Federal Statutory Rate to Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
U.S. federal tax benefit at statutory rate 21.00% 21.00%
State income taxes, net of federal benefit 11.80% 3.50%
Non-deductible expenses and other (0.30%) 0.30%
Stock-based compensation (1.10%) (1.50%)
Research and development credits 1.20% 2.50%
Transaction cost 3.90% 0.00%
Foreign rate differential (3.10%) (4.30%)
Change in valuation allowance, net (33.40%) (21.50%)
Effective tax rate 0.00% 0.00%