XML 48 R6.htm IDEA: XBRL DOCUMENT v3.24.0.1
Consolidated Statements of Shareholders’ Equity - USD ($)
$ in Thousands
Total
At-The-Market Offering
Private Investment In Public Entity Offering
2020 Award
ADDITIONAL PAID-IN CAPITAL
ADDITIONAL PAID-IN CAPITAL
At-The-Market Offering
ADDITIONAL PAID-IN CAPITAL
Private Investment In Public Entity Offering
ADDITIONAL PAID-IN CAPITAL
2020 Award
ACCUMULATED OTHER COMPREHENSIVE INCOME/(LOSS)
ACCUMULATED DEFICIT
ORDINARY SHARES
ORDINARY SHARES
COMMON STOCK
ORDINARY SHARES
COMMON STOCK
At-The-Market Offering
ORDINARY SHARES
COMMON STOCK
Private Investment In Public Entity Offering
ORDINARY SHARES
COMMON STOCK
2020 Award
DEFERRED SHARES
DEFERRED SHARES
COMMON STOCK
Beginning balance (in shares) at Dec. 31, 2020                       35,930,331         1
Beginning balance at Dec. 31, 2020 $ 196,561       $ 279,480       $ 14,585 $ (97,899)   $ 367         $ 28
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Exercise of share options (in shares)                     1,476,936 1,244,709          
Exercise of share options 1,905       1,891             $ 14          
Issuance of ordinary shares under ATM facility or PIPE offering, net of issuance costs (in shares)                       4,600,000     232,227    
Issuance of ordinary shares under ATM facility or PIPE offering, net of issuance costs (in shares) 154,794     $ 0 154,743     $ (3)       $ 51     $ 3    
Issuance of ordinary shares to settle vested restricted stock units (in shares)                     12,607 12,607          
Share-based compensation expense 8,639       8,639                        
Unrealized loss on foreign currency translation (5,745)               (5,745)                
Net loss (71,742)                 (71,742)              
Ending balance (in shares) at Dec. 31, 2021                       42,019,874         1
Ending balance at Dec. 31, 2021 284,412       444,750       8,840 (169,641)   $ 435         $ 28
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Exercise of share options (in shares)                     462,722 462,722          
Exercise of share options 401       397             $ 4          
Issuance of ordinary shares under ATM facility or PIPE offering, net of issuance costs (in shares)                       44,416          
Issuance of ordinary shares under ATM facility or PIPE offering, net of issuance costs (in shares) 440       439             $ 1          
Issuance of ordinary shares to settle vested restricted stock units (in shares)                     24,747 82,622          
Issuance of ordinary shares under employee share purchase plan (in shares)                       22,160          
Issuance of ordinary shares under employee share purchase plan 199       199                        
Shares tendered for withholding taxes 83       83                        
Share-based compensation expense 13,123       13,123                        
Unrealized loss on foreign currency translation (25,707)               (25,707)                
Net loss (91,505)                 (91,505)              
Ending balance (in shares) at Dec. 31, 2022                     42,631,794 42,631,794       1 1
Ending balance at Dec. 31, 2022 $ 181,280       458,825       (16,867) (261,146)   $ 440         $ 28
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Exercise of share options (in shares) 166,801                   166,801 166,801          
Exercise of share options $ 2                     $ 2          
Issuance of ordinary shares under ATM facility or PIPE offering, net of issuance costs (in shares)                         2,937,622 16,076,750      
Issuance of ordinary shares under ATM facility or PIPE offering, net of issuance costs (in shares)   $ 28,120 $ 116,815     $ 28,091 $ 116,652           $ 29 $ 163      
Issuance of warrants to purchase ordinary shares 687       687                        
Issuance of ordinary shares to settle vested restricted stock units (in shares)                     69,120 78,022          
Issuance of ordinary shares to settle vested restricted stock units 0       (1)             $ 1          
Cancellation of deferred share (in shares)                                 (1)
Cancellation of deferred share 0       28                       $ (28)
Issuance of ordinary shares under employee share purchase plan (in shares)                       52,482          
Issuance of ordinary shares under employee share purchase plan 351       351                        
Shares tendered for withholding taxes 265       265                        
Share-based compensation expense 17,277       17,277                        
Unrealized loss on foreign currency translation (59)               (59)                
Net loss (118,464)                 (118,464)              
Ending balance (in shares) at Dec. 31, 2023                     61,943,471 61,943,471       0 0
Ending balance at Dec. 31, 2023 $ 225,744       $ 621,645       $ (16,926) $ (379,610)   $ 635         $ 0