Collaborations - Change in Accounts Receivable, Contract Asset and Liabilities (Details) $ in Thousands	9 Months Ended
	Sep. 30, 2023 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts receivable and contract assets, Beginning balance	$ 2,537
Accounts receivable and contract assets, Additions	21,199
Accounts receivable and contract assets, Deductions	(19,958)
Accounts receivable and contract assets, Ending balance	3,778
Contract Liabilities, Beginning balance	63,260
Contract Liabilities, Additions	11,220
Contract Liabilities, Deductions	(30,707)
Contract Liabilities, Ending balance	43,773
Billed Receivables - Sanofi
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts receivable and contract assets, Beginning balance	0
Accounts receivable and contract assets, Additions	9,979
Accounts receivable and contract assets, Deductions	(9,979)
Accounts receivable and contract assets, Ending balance	0
Unbilled Receivables - Sanofi
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Accounts receivable and contract assets, Beginning balance	2,537
Accounts receivable and contract assets, Additions	11,220
Accounts receivable and contract assets, Deductions	(9,979)
Accounts receivable and contract assets, Ending balance	3,778
Deferred Revenue - Vertex
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contract Liabilities, Beginning balance	8,399
Contract Liabilities, Additions	0
Contract Liabilities, Deductions	(8,399)
Contract Liabilities, Ending balance	0
Deferred Revenue - Sanofi
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contract Liabilities, Beginning balance	54,861
Contract Liabilities, Additions	11,220
Contract Liabilities, Deductions	(22,308)
Contract Liabilities, Ending balance	$ 43,773