EXHIBIT 32.1

CERTIFICATION OF CHIEF EXECUTIVE OFFICER PURSUANT TO

18 U.S.C. SECTION 1350, AS ADOPTED PURSUANT TO SECTION 906 OF

THE SARBANES-OXLEY ACT OF 2002

The following certification is hereby made in connection with the Quarterly Report on Form 10-Q for the quarter period ended March 31, 2023 of Tempo Automation Holdings, Inc. (the “Company”) as filed with the Securities and Exchange Commission on the date hereof (the “Report”):

I, Joy Weiss, President and Chief Executive Officer, hereby certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that, to the best of my knowledge:

1. The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and

2. The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date: May 15, 2023	By:	/s/ Joy Weiss
		Joy Weiss
		President and Chief Executive Officer
		(Principal Executive Officer)