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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2020 $ 763,293 $ 90 $ 1,167,367 $ 64 $ (404,228)
Beginning balance, shares at Dec. 31, 2020   89,906,835      
Issuance of common stock upon acquisition of ZebiAI 62,992 $ 2 62,990    
Issuance of common stock upon acquisition of ZebiAI, shares   1,914,219      
Issuance of common stock through follow-on/at-the-market offerings, net 382,210 $ 15 382,195    
Issuance of common stock through follow-on/at-the-market offerings, net shares   15,188,679      
Issuance of common stock through exercise of stock options 4,739 $ 1 4,738    
Issuance of common stock through exercise of stock options, shares   996,536      
Issuance of common stock via employee stock purchase plan 1,141 $ 1 1,140    
Issuance of common stock via employee stock purchase plan, shares   43,685      
Vesting of restricted common stock 3   3    
Vesting of restricted common stock ,shares   84,489      
Vesting of restricted stock units, Shares   75,875      
Stock compensation expense 48,454   48,454    
Unrealized (loss) gain on investments (1,152)     (1,152)  
Net loss (363,872)       (363,872)
Ending balance at Dec. 31, 2021 897,808 $ 109 1,666,887 (1,088) (768,100)
Ending balance, shares at Dec. 31, 2021   108,210,318      
Issuance of common stock upon milestone achievement,shares   301,939      
Issuance of common stock upon milestone achievement 6,203   6,203    
Issuance of common stock through follow-on/at-the-market offerings, net 284,744 $ 11 284,733    
Issuance of common stock through follow-on/at-the-market offerings, net shares   11,320,755      
Issuance of common stock through exercise of stock options 3,480 $ 1 3,479    
Issuance of common stock through exercise of stock options, shares   757,873      
Issuance of common stock via employee stock purchase plan 1,686   1,686    
Issuance of common stock via employee stock purchase plan, shares   123,019      
Vesting of restricted stock units, Shares   398,330      
Stock compensation expense 56,138   56,138    
Unrealized (loss) gain on investments (9,332)     (9,332)  
Net loss (290,509)       (290,509)
Ending balance at Dec. 31, 2022 950,218 $ 121 2,019,126 (10,420) (1,058,609)
Ending balance, shares at Dec. 31, 2022   121,112,234      
Issuance of common stock upon milestone achievement,shares   1,797,064      
Issuance of common stock upon milestone achievement 12,750 $ 2 12,748    
Issuance of common stock through follow-on/at-the-market offerings, net 30,281 $ 3 30,278    
Issuance of common stock through follow-on/at-the-market offerings, net shares   3,026,072      
Issuance of common stock through exercise of stock options 1,986 $ 1 1,985    
Issuance of common stock through exercise of stock options, shares   399,498      
Issuance of common stock via employee stock purchase plan 2,486   2,486    
Issuance of common stock via employee stock purchase plan, shares   244,125      
Vesting of restricted stock units, Shares   883,416      
Stock compensation expense 86,031   86,031    
Unrealized (loss) gain on investments 10,224     10,224  
Net loss (341,973)       (341,973)
Ending balance at Dec. 31, 2023 $ 752,003 $ 127 $ 2,152,654 $ (196) $ (1,400,582)
Ending balance, shares at Dec. 31, 2023   127,462,409