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INCOME TAXES - Narrative (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2016
Income Tax Contingency [Line Items]          
Provision for (benefit from) income taxes $ 49,000 $ (188,000) $ 23,000    
Effective income tax rate 0.00% 0.00% 0.00%    
Undistributed earnings of foreign subsidiaries $ 0 $ 0      
Valuation allowance 672,898,000 360,573,000      
Increase valuation allowance for deferred tax assets 312,300,000 185,800,000      
Operating loss carryforwards, amount nullified by ownership change         $ 12,000,000
Tax credit carryforward, amount nullified by ownership change         15,000,000
Net tax credit amount nullified by ownership change         $ 3,000,000
Unrecognized tax benefits 72,330,000 42,894,000 $ 20,635,000 $ 11,647,000  
Unrecognized tax benefits that would impact effective tax rate 500,000 $ 2,600,000 $ 2,600,000    
Unrecognized tax benefits, interest on income taxes accrued 60,000        
Unrecognized tax benefits, income tax penalties accrued 7,000        
Federal          
Income Tax Contingency [Line Items]          
Operating loss carryforwards 2,003,000,000        
Federal | Research Tax Credit Carryforward          
Income Tax Contingency [Line Items]          
Tax credit carryforward, amount 80,500,000        
State          
Income Tax Contingency [Line Items]          
Operating loss carryforwards 922,700,000        
State | Research Tax Credit Carryforward          
Income Tax Contingency [Line Items]          
Tax credit carryforward, amount 63,100,000        
Foreign          
Income Tax Contingency [Line Items]          
Operating loss carryforwards $ 2,000,000.0