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Stock-based compensation - Schedule of Fair Value Assumptions for Stock Options Granted (Details) - $ / shares
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Risk-free interest rate   1.40%
Risk-free interest rate, Minimum 0.42%  
Risk-free interest rate, maximum 0.71%  
Expected term (in years) 6 years 5 years
Expected volatility   90.00%
Expected Volatility, minimum 99.00%  
Expected Volatility, maximum 100.00%  
Estimated fair value of common stock   $ 2.95
Minimum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Estimated fair value of common stock $ 32.00  
Maximum    
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Estimated fair value of common stock $ 41.58