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Collaboration and License Agreement - Additional Information (Details) - Bristol-Myers Squibb Company - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
May 31, 2021
Jun. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2021
Dec. 31, 2020
May 31, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Non-refundable upfront payment received     $ 50,000   $ 50,000        
Options to License Druggable Target Lesions                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Non-refundable upfront payment received     31,148   31,148        
Collaboration and License Agreement                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Collaboration term expiration period 42 months                
Initial nonrefundable upfront fee received   $ 50,000              
Non-refundable upfront payment received                 $ 50,000
Deferred revenue recognized     300 $ 0 700 $ 0      
Deferred revenue     49,100   49,100     $ 49,900  
Deferred revenue, current     8,900   8,900     2,100  
Deferred revenue, noncurrent     $ 40,200   $ 40,200     $ 47,800  
Collaboration and License Agreement | Options to License Druggable Target Lesions | Scenario Forecast                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Milestone payments entitled to be received             $ 6,500    
Collaboration and License Agreement | Maximum                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Milestone payments entitled to be received                 301,000
Collaboration and License Agreement | Maximum | Research, Development and Regulatory Milestones                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Milestone payments entitled to be received                 176,000
Collaboration and License Agreement | Maximum | Commercial Milestones                  
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                  
Milestone payments entitled to be received                 $ 125,000