Exhibit 99.1

MEDICENNA THERAPEUTICS CORP.

(the “Corporation”)

NOTICE OF CHANGE OF AUDITOR

TO:	Alberta Securities Commission
	British Columbia Securities Commission
	Ontario Securities Commission

AND TO: PricewaterhouseCoopers LLP (“PwC”)

Pursuant to National Instrument 51-102 – Continuous Disclosure Obligations (“NI 51-102”), the Corporation hereby gives notice as follows:

1.             On December 20, 2023, PwC resigned as auditor of the Corporation.

2.             There were no reservations or modified opinions contained in PwC’s report on the financial statements of the Corporation or its predecessor for the financial years ended March 31, 2023 or March 31, 2022.

3.             In the opinion of the board of directors of the Corporation (the “Board”), there have been no “reportable events” as such term is defined in NI 51-102, between the Corporation and PwC.

4.             Following the resignation of PwC, the contents and filing of this notice have been recommended by the audit committee of the Corporation and approved by the Board.

Dated this 20^th day of December, 2023.

MEDICENNA THERAPEUTICS CORP.

Per:	(s) Fahar Merchant
	Name:	Fahar Merchant
	Title:	President and Chief Executive Officer