Fair Value Measurements and Financial Instruments - Summary of Change in Carrying Value of Level 3 Financial Instruments (Details) - USD ($) $ in Thousands		1 Months Ended	12 Months Ended
	Jun. 02, 2021	Sep. 30, 2022	Dec. 31, 2022	Dec. 31, 2021
MorphoSys
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Maximum commitment to fund collaborative arrangement				$ 150,000
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | MorphoSys
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Maximum commitment to fund collaborative arrangement	$ 150,000	$ 150,000	$ 150,000
Equity Securities | Level 3
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at the beginning of the year			43,013	0
Purchases			28,785	35,120
(Losses)/gains on equity securities			(22,634)	7,893
Transfers out of Level 3			(40,692)
Balance at the end of the year			8,472	43,013
Debt Securities | Level 3
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at the beginning of the year			253,700	214,400
Purchases			479,559	70,441
Gains/(losses) on initial recognition			600
Unrealized gains on available for sale debt securities included in other comprehensive losses			24,000	11,600
Losses/(gains) on available for sale debt securities included in earnings			(67,800)	1,300
Settlement of forwards			79,585	18,459
Redemption			(542,044)	(62,500)
Balance at the end of the year			227,600	253,700
Forwards | Level 3
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at the beginning of the year			16,700	18,600
Losses/(gains) on available for sale debt securities included in earnings			62,885	16,559
Settlement of forwards			(79,585)	(18,459)
Balance at the end of the year			0	16,700
Funding Commitments | Level 3
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at the beginning of the year			0
Gains/(losses) on initial recognition			(9,400)
Losses/(gains) on available for sale debt securities included in earnings			6,900
Balance at the end of the year			(2,500)	0
Derivative Instruments | Level 3
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at the beginning of the year			0
Gains on derivative financial instruments			96,610
Balance at the end of the year			96,610	0
Royalty at Fair Value | Level 3
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance at the beginning of the year			0
Purchases			21,215
Other non-operating expense			(6,715)
Balance at the end of the year			$ 14,500	$ 0